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24-hour urine cortisone test for adrenal hormone imbalance and high blood pressure symptoms

Cortisone 24-Hour Urine Test — Adrenal & Blood Pressure Check

Cortisone, 24-Hour Urine

  • Screen for unexplained high blood pressure
  • Check hormone breakdown and potassium balance
  • Monitor stress hormone processing over time
$1010
LegitScript certified merchant
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained high blood pressure, muscle weakness, or low potassium levels that haven't been explained by other causes. It's often used alongside a urine cortisol test to check how your body processes stress hormones. This combination can help identify rare conditions where your body doesn't properly break down cortisol, causing it to build up and affect your blood pressure and mineral balance.

How should I prepare for this test?

How can I naturally support healthy cortisol and cortisone balance? Cutting back on licorice, licorice-flavored candy, and certain herbal supplements can help since these are known to interfere with how your body processes cortisol. Managing stress through regular sleep, exercise, and relaxation techniques can also support balanced cortisol levels naturally. Staying hydrated and maintaining a diet rich in potassium (like bananas and leafy greens) may help support healthy blood pressure while you investigate further.

What's included in this test?

This test measures cortisone, a byproduct your body creates when breaking down the stress hormone cortisol. Checking this helps show whether your body is properly clearing cortisol or whether it's building up and causing problems with blood pressure and potassium levels.

What happens after I get my results?
Your results will show up in your account with the normal range for cortisone clearly explained so you know exactly where you stand. If your cortisol-to-cortisone ratio looks unusual, next steps might include cutting out licorice products or other foods that can skew results, then retesting to confirm the pattern. If your results show dangerously high blood pressure or very low potassium, seek medical care right away. You can download a standard lab report from your account anytime, and use the trends feature to track your levels if you test again in the future.
When will I get my results?
Results are typically ready within about 7 days after your lab visit. Once processed, you'll get a notification and can log into your account to view the full report right away.
Who should consider this test?
This test is worth considering if you have high blood pressure that hasn't responded well to typical treatments, especially when paired with low potassium levels. It's also useful if you have a family history of rare adrenal or blood pressure disorders. People who consume large amounts of licorice products and experience unexplained blood pressure changes may also benefit from this test.
What symptoms indicate I may need this test?
Common signs include high blood pressure that's hard to control, muscle weakness or cramping, fatigue, and excessive thirst or urination. Some people also notice tingling sensations or heart palpitations, which can be linked to low potassium. If you're experiencing several of these symptoms together, this test can help figure out if a cortisol-processing issue is the cause.
What is cortisone and why does it matter?
Cortisone is what's left over after your body breaks down cortisol, your main stress hormone. Normally, an enzyme in your kidneys converts cortisol into cortisone to keep cortisol from overactivating certain receptors that control blood pressure and mineral balance. When this conversion doesn't happen properly, cortisol builds up and can cause high blood pressure and other health issues, which is why measuring cortisone helps show if this process is working correctly.
What does a high cortisol-to-cortisone ratio mean?
A high ratio suggests your body isn't converting cortisol into cortisone as efficiently as it should, allowing cortisol to build up. This buildup can cause your body to act like it has too much of a related hormone called aldosterone, leading to high blood pressure and low potassium. This pattern can be caused by a rare inherited condition or by eating large amounts of licorice or similar substances that block the conversion process.
How often should I retest?
If your first results are unusual, retesting after removing potential dietary triggers like licorice for a few weeks is a reasonable next step to see if levels normalize. For ongoing monitoring, retesting every few months can help you track whether lifestyle changes are making a difference. Using the trends feature in your account makes it easy to compare results over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Cortisone (24-Hour Urine) 45 mcg/24hr
Demo results
Low Normal High
45 mcg/24hr

What this means

A cortisone level below the normal range may suggest your body isn't converting cortisol into cortisone efficiently, which can allow cortisol to build up. This pattern, especially when paired with a high cortisol-to-cortisone ratio, is often seen in conditions that cause high blood pressure and low potassium.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Cortisone 24-Hour Urine Test — Adrenal & Blood Pressure Check

  • Screen for unexplained high blood pressure
  • Check hormone breakdown and potassium balance
  • Monitor stress hormone processing over time
$1010
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.