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24-hour urine cortisol test for adults with stress, weight gain, or Cushing's symptoms

24-Hour Urine Cortisol Test for Cushing's Symptoms

Cortisol, Free And Cortisone, 24 Hour Urine with Creatinine

  • Detect excess stress hormone levels
  • Screen for Cushing's syndrome signs
  • Monitor weight gain hormone causes
$1713
LegitScript certified merchant
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained weight gain, especially around your belly and face, along with muscle weakness, easy bruising, or stretch marks. It's also useful if you have high blood pressure or blood sugar that doesn't have a clear cause. This test helps identify whether your body is producing too much cortisol, the hormone your body releases in response to stress.

What's included in this test?

This test measures free cortisol and cortisone in a 24-hour urine sample, plus creatinine to confirm the sample was collected correctly and completely. Cortisol is your body's main stress hormone, and cortisone is a related form your body converts it to and from. Looking at both together, along with creatinine, gives a fuller picture of how your body is managing cortisol over a full day rather than just one moment in time.

What happens after I get my results?

Your results will show up in your account with each value's normal range clearly explained, so you can see exactly where you stand. If your free cortisol or cortisone levels are outside the normal range, next steps often include reducing stress, improving sleep, and cutting back on alcohol or intense exercise before retesting in a few weeks. If a value comes back very high, it's a good idea to seek medical care promptly since it may point to a condition that needs further evaluation. You can download a standard lab report from your account anytime, and the trends feature lets you track your cortisol levels over time.

How can I naturally support healthy cortisol levels?
Getting consistent, good-quality sleep is one of the best ways to help your body regulate cortisol naturally. Regular moderate exercise, like walking or yoga, can lower chronically high cortisol, while overtraining can actually raise it. Cutting back on caffeine and alcohol, practicing deep breathing or meditation, and eating regular balanced meals also help keep cortisol in a healthy range.
When will I get my results?
Results are typically ready within about 7 days after your 24-hour urine sample is received at the lab. You'll get a notification once they're available, and you can log into your account to view them anytime. The report will break down each marker along with what the numbers mean.
Who should consider this test?
This test is a good fit for anyone with symptoms of excess cortisol, such as sudden weight gain, thin skin, muscle weakness, or high blood pressure that hasn't responded to typical lifestyle changes. It's also useful for people whose doctors have ruled out other causes for these symptoms and want to check their cortisol output over a full day. Athletes or highly stressed individuals wanting to understand how chronic stress may be affecting their hormones may also benefit.
What symptoms indicate I may need this test?
Common symptoms include rapid weight gain (especially in the face, neck, and abdomen), purple stretch marks, easy bruising, muscle weakness, and high blood pressure. Fatigue that doesn't improve with rest, mood changes, and irregular periods in women can also be signs. If you're noticing several of these symptoms together, this test can help clarify what's going on.
What does high cortisol mean?
A high result means your body is producing more cortisol than it should over a 24-hour period. This can happen from chronic stress, certain medications like steroids, or less commonly from a condition called Cushing's syndrome where your body makes too much cortisol on its own. Lifestyle changes like better sleep, stress reduction, and cutting back on stimulants can help, but a significantly elevated result is worth addressing with prompt medical attention.
What does low cortisol mean?
A low result means your body isn't producing enough cortisol, which can leave you feeling extremely tired, dizzy, or unable to handle stress well. This can be linked to adrenal gland issues or other underlying conditions affecting hormone production. If your levels are very low along with symptoms like severe fatigue or fainting, it's important to seek medical care right away.
How often should I retest?
If your first result is in the normal range and you have no ongoing symptoms, you likely don't need to retest unless new symptoms appear. If your levels were borderline or you made lifestyle changes to address high or low cortisol, retesting in 4 to 8 weeks can help you see if those changes are working. Tracking results over time using the trends feature makes it easier to spot patterns.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Free Cortisol (24-Hour Urine) 85 mcg/24hr
Demo results
Low (<4 mcg/24hr) Normal (4-50 mcg/24hr) High (>50 mcg/24hr)
85 mcg/24hr

What this means

This result is above the typical range, suggesting your body may be producing more cortisol than normal over a 24-hour period. This can be caused by chronic stress, certain medications, or in some cases an underlying condition affecting your adrenal glands. A significantly elevated result like this is worth addressing promptly.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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24-Hour Urine Cortisol Test for Cushing's Symptoms

  • Detect excess stress hormone levels
  • Screen for Cushing's syndrome signs
  • Monitor weight gain hormone causes
$1713
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.