What's this test for?

This test is ideal if you're experiencing unexplained joint pain, recurring infections, fatigue, or symptoms that suggest your immune system isn't working right. It's also useful if you have a personal or family history of autoimmune conditions like lupus or rheumatoid arthritis, or if you've been told you might have a complement deficiency. The CH50 test checks how well a key part of your immune system, called the complement system, is functioning overall.

What's included in this test?

This test measures your total complement activity as a single combined score, rather than a list of individual biomarkers. It works by checking whether all the different complement proteins in your blood system are functioning together properly to help your immune system fight infections and clear damaged cells.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what's considered a normal range and where your value falls. If your levels are outside the normal range, the report will explain simple next steps, such as retesting or watching for related symptoms, and will flag if a value is severe enough that you should seek medical care right away. You can download a standard lab report from your account at any time, and if you retest in the future, the trends feature lets you track how your levels change over time.

How can I naturally support immune system health?

Getting enough sleep, staying hydrated, and eating a diet rich in fruits, vegetables, and lean protein all help your immune system function well. Regular moderate exercise and managing stress through activities like walking, meditation, or yoga can also support healthy immune activity. Avoiding smoking and limiting alcohol intake are two of the most impactful changes you can make for long-term immune health.

When will I get my results?

Results are typically ready within about 7 days of your blood draw. You'll get a notification as soon as your report is available in your account, so there's no need to call or follow up.

Who should consider this test?

People with symptoms of chronic infections, unexplained inflammation, or a family history of autoimmune diseases like lupus or rheumatoid arthritis may want to consider this test. It's also useful for anyone already diagnosed with an autoimmune or kidney condition who wants to monitor how active their disease is over time. If you've had recurring infections that seem hard to explain, this test can help check whether your immune system's complement pathway is working normally.

What symptoms indicate I may need this test?

Common symptoms that might point to a complement system issue include frequent or unusual infections, joint pain and swelling, unexplained skin rashes, or swelling episodes. Fatigue and signs of kidney problems, like foamy urine or swelling in the legs, can also be reasons to check your complement levels. If you've already been diagnosed with an autoimmune condition and are having a flare-up, this test can help show how active the condition currently is.

What does high total complement mean?

A high CH50 result can happen during acute inflammation, certain cancers like leukemia or Hodgkin's disease, or conditions like Behcet's disease. This usually means your immune system is in an active, revved-up state responding to something in your body. Simple next steps include noting any current symptoms of infection or inflammation and considering a retest once any acute illness has passed to see if levels return to normal.

What does low total complement mean?

Low complement levels can be linked to genetic deficiencies, liver disease, kidney inflammation, lupus, rheumatoid arthritis, or certain types of anemia. It generally means part of your immune defense system has less capacity than normal, which can make you more prone to infections or reflect an ongoing autoimmune process. If your result is low, it's worth tracking your symptoms closely and retesting periodically, and seeking medical care promptly if you notice signs of a serious infection.

How often should I retest?

If your first result is normal and you have no ongoing symptoms, you likely don't need to retest unless new symptoms appear. If you have an autoimmune condition or a known complement issue, retesting every few months, or whenever you have a flare-up, can help you and track how your condition is behaving. Use the trends feature in your account to compare results over time and spot patterns.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Total Complement CH50 Test - Immune System Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]