What's this test for?

This test is ideal if you've been diagnosed with metastatic colorectal cancer and are trying to figure out whether EGFR-targeted therapy will work for you. It looks at tumor tissue for specific gene changes that can predict whether certain treatments are likely to help or are unlikely to be effective. This helps guide treatment planning so you can avoid therapies that may not work for your specific tumor type.

How should I prepare for this test?

See the pre-collection instructions on your order confirmation.

What's included in this test?

This panel checks four different genes that are commonly altered in colorectal tumors. Each gene plays a role in cell growth signaling, and changes in these genes can affect whether EGFR-targeted treatments will work well for a particular tumor. Testing all four together gives a fuller picture of the tumor's biology than looking at just one gene alone.

What happens after I get my results?

Your results will be available in your account, with each mutation status clearly explained so you understand what was found. If a mutation is detected, the report will note that certain EGFR-targeted therapies may be less effective, which is useful information for treatment planning going forward. The standard lab report can be downloaded directly from your account for your records. Since this is a one-time tumor tissue analysis, ongoing tracking isn't typically needed the way it is for blood biomarkers, but any related future test results can still be viewed over time through the trends feature.

When will I get my results?

Results are typically ready within about 7 days after your sample is processed by the lab. This timeframe reflects the detailed genetic analysis needed to check each of the four genes in the panel. You'll be notified as soon as your results are available in your account.

Who should consider this test?

This test is most relevant for people who have been diagnosed with metastatic colorectal cancer and are considering EGFR-targeted therapy as part of their treatment plan. It's also useful for those who want to understand more about their tumor's genetic makeup before starting a new treatment course. This is a specialized test, not a general screening tool for people without a colorectal cancer diagnosis.

What is EGFR-targeted therapy and why does this panel matter?

EGFR-targeted therapy is a type of treatment that blocks a specific growth signal that some colorectal tumors depend on to grow. This panel matters because certain gene mutations can make tumors resistant to this type of treatment, meaning the therapy wouldn't work well even though it might seem like a good option otherwise. Knowing your tumor's mutation status ahead of time helps avoid starting a treatment that's unlikely to be effective.

What does it mean if a mutation is found?

If one of the four genes shows a mutation, it generally means the tumor is less likely to respond well to EGFR-targeted therapies. It can also mean the tumor may behave more aggressively compared to tumors without these mutations. This doesn't rule out other treatment options — it simply helps narrow down which treatments are more likely to be effective for your specific case.

What does it mean if no mutations are found?

If none of the four genes show mutations, this is generally considered a favorable result for EGFR-targeted therapy, meaning this treatment approach may work well for you. It suggests the tumor doesn't have the specific resistance patterns linked to these genes. This information can support moving forward with EGFR-targeted treatment as part of your care plan.

What should I do if my results show a mutation?

If a mutation is found, the most important next step is discussing alternative treatment options that don't rely on EGFR-targeting, since your tumor may not respond well to that approach. Keep a copy of your report handy, as it contains detailed information that will be useful for planning next steps. Because this affects active cancer treatment decisions, it's important to act on these results promptly rather than delaying.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Colorectal Cancer Mutation Panel - EGFR Therapy Guide

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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