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Chronic urticaria autoimmune blood test for people with persistent unexplained hives

Chronic Urticaria Autoimmune Blood Test

Chronic Urticaria Panel 3

  • Screen for autoimmune hives triggers
  • Detect chronic unexplained skin flare-ups
  • Track recurring hives over time
$1010
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing hives that keep coming back for weeks or months without a clear cause, like a food or medication trigger. Chronic hives can sometimes be driven by your own immune system attacking itself, and this test helps identify whether that autoimmune pattern is behind your symptoms. It's especially useful if typical allergy tests haven't given you any answers.

What's included in this test?

This test checks for autoantibodies that cause your immune system to release histamine, the chemical responsible for hives, itching, and swelling. Because a positive result doesn't identify the exact antibody involved, the test focuses on confirming whether an autoimmune process is happening at all, which helps guide how you and any future testing approach your chronic hives.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what a positive or negative result means. If your result is positive, it points to an autoimmune cause for your hives, and next steps often include tracking flare patterns, avoiding known triggers like stress or certain medications, and retesting if your symptoms change significantly. You can download a standard lab report from your account at any time, and the trends feature lets you track this and other results over time. If your hives are severe, involve swelling of the throat or trouble breathing, seek medical care right away.

How can I naturally support my skin and immune response with chronic hives?
While you can't cure an autoimmune trigger with lifestyle changes alone, you can reduce flare-ups by managing stress, since stress hormones can worsen histamine release. Keeping a symptom diary to spot patterns with heat, tight clothing, alcohol, or certain foods can help you avoid triggers. Cool compresses, loose breathable clothing, and staying hydrated can ease itching during a flare, and some people find relief by cutting back on high-histamine foods like aged cheese and processed meats.
When will I get my results?
Results are typically ready within about 7 days of your lab visit. Once processed, they'll be posted directly to your secure online account, where you can view and download them at your convenience.
Who should consider this test?
This test is a good option for anyone dealing with hives that show up almost daily for six weeks or longer without an obvious cause. It's also useful if you've already ruled out food allergies, medications, or infections as triggers and want to explore whether an autoimmune process is involved.
What symptoms indicate I may need this test?
Watch for hives that appear, disappear, and reappear over weeks or months, often with no clear pattern. Other signs include itchy welts that shift location on your body, swelling around the eyes or lips, and hives that flare with stress, heat, or tight clothing. If antihistamines only partially help or symptoms keep returning, this test can offer useful insight.
What does a positive result mean?
A positive result means your immune system is likely producing antibodies that trigger histamine release on its own, without an outside allergen. This tells you your hives have an autoimmune basis rather than being caused by a food, medication, or environmental allergen. It doesn't identify the exact antibody, but it confirms the general mechanism behind your symptoms.
How often should I retest?
Most people don't need to retest this specific panel frequently, since a positive or negative autoimmune result doesn't typically change quickly. However, if your symptoms change dramatically, resolve completely, or new treatments are introduced, retesting can help confirm whether the underlying process has shifted.
What should I do if my results are abnormal?
If your result is positive, start tracking your flare triggers and consider lifestyle changes like stress reduction and avoiding known irritants such as heat or tight clothing. Keep a symptom log to share as part of your ongoing care planning, and use the trends feature to monitor whether your symptoms and future test results change over time. If hives are ever accompanied by swelling of the face, throat, or difficulty breathing, seek emergency medical care immediately.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Chronic Urticaria Autoantibody (Histamine Release Test) Negative
Demo results
Negative Positive
Negative

What this means

A negative result means no autoimmune trigger for histamine release was detected, so your hives are less likely to have an autoimmune cause. This suggests other triggers, like foods, medications, or environmental factors, may be worth exploring instead.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Chronic Urticaria Autoimmune Blood Test

  • Screen for autoimmune hives triggers
  • Detect chronic unexplained skin flare-ups
  • Track recurring hives over time
$1010
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.