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Chromogranin A test for detecting neuroendocrine tumors and monitoring treatment progress

Chromogranin A Test for Tumor Marker Screening

Chromogranin A, LC/MS/MS

Google
3,138 reviews
  • Measures stress hormone levels
  • Checks for certain tumor markers
  • Assesses neuroendocrine activity
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing symptoms like flushing, diarrhea, wheezing, or heart palpitations that may indicate a neuroendocrine tumor or carcinoid syndrome. It's also used to monitor people already diagnosed with these conditions to track tumor activity and treatment effectiveness. Many doctors order this test when other imaging or symptoms suggest a neuroendocrine tumor, or to check if cancer treatment is working.

What's included in this test?

This test measures chromogranin A, a protein released by neuroendocrine cells that can be elevated when certain tumors are present. It's particularly useful for detecting carcinoid tumors, pancreatic neuroendocrine tumors, and other neuroendocrine cancers, as well as monitoring how well treatment is working. The LC/MS/MS method provides highly accurate measurements that aren't affected by common medications like proton pump inhibitors, making it more reliable than standard immunoassay methods.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your chromogranin A level means for your health and whether further evaluation is needed. These notes include personalized recommendations such as follow-up imaging, additional tests, or when to consult an oncologist or endocrinologist. You'll also get the standard lab report and can track your chromogranin A levels over time using our trends feature, which is especially helpful for monitoring tumor activity or treatment response.

Who should consider getting this test?
This test is important for people experiencing unexplained flushing, persistent diarrhea, or wheezing that might indicate carcinoid syndrome. It's also essential for those already diagnosed with neuroendocrine tumors who need to monitor disease progression or treatment response. Anyone with a family history of neuroendocrine cancers or symptoms suggestive of these conditions should discuss this test with their doctor.
What symptoms indicate I may need this test?
Common symptoms include facial flushing (especially after eating or drinking), chronic diarrhea, wheezing or difficulty breathing, rapid heartbeat, and unexplained weight loss. Some people experience skin rashes, low blood pressure, or abdominal pain. These symptoms can occur with carcinoid syndrome or neuroendocrine tumors, though they can also be caused by other conditions, so testing helps determine the cause.
What is chromogranin A and why does it matter?
Chromogranin A is a protein found in neuroendocrine cells throughout your body, including in your digestive system, lungs, and other organs. When neuroendocrine tumors develop, they often produce excess chromogranin A, making it a valuable marker for detecting and monitoring these cancers. Elevated levels can indicate tumor presence, growth, or spread, while decreasing levels during treatment suggest the therapy is working.
What does high chromogranin A mean?
High chromogranin A levels may indicate the presence of a neuroendocrine tumor, carcinoid syndrome, or other neuroendocrine conditions. However, levels can also be elevated due to kidney disease, inflammatory bowel disease, chronic stress, or certain medications. Your doctor will consider your symptoms, medical history, and additional tests to determine the cause and appropriate next steps.
What causes high chromogranin A levels?
The most concerning cause is neuroendocrine tumors, including carcinoid tumors and pancreatic neuroendocrine cancers. However, elevated levels can also result from kidney failure, liver disease, inflammatory conditions like Crohn's disease, chronic gastritis, or even severe stress. Some medications, particularly older types of acid-blocking drugs, can raise levels, though the LC/MS/MS method used in this test minimizes this interference.
How often should I retest chromogranin A?
If you're newly diagnosed with a neuroendocrine tumor, your doctor may test every 3-6 months to monitor tumor activity and treatment response. For those in remission or on stable treatment, testing every 6-12 months is common. If you're being evaluated for a suspected tumor and initial results are normal but symptoms persist, your doctor may recommend retesting in a few months or ordering additional diagnostic tests.
What should I do if my chromogranin A is high?
First, don't panic—elevated levels don't always mean cancer and require careful evaluation. Schedule an appointment with your doctor to discuss results and determine if additional testing like imaging scans (CT, MRI, or PET) or other tumor markers are needed. If a neuroendocrine tumor is confirmed, your doctor will refer you to an oncologist or endocrinologist who specializes in these conditions. Avoiding stress, managing any inflammatory conditions, and reviewing your medications with your doctor can also help clarify the cause.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
Chromogranin A 185 ng/mL
Demo results
Normal < 95 Elevated ≥ 95
185 ng/mL

What this means

Your chromogranin A level is elevated above the normal range. While this may indicate neuroendocrine activity or tumor presence, it can also be elevated due to kidney issues, inflammatory conditions, or stress. Your doctor will likely recommend additional testing or imaging to determine the underlying cause.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
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Chromogranin A Test for Tumor Marker Screening

Google
3,138 reviews
  • Measures stress hormone levels
  • Checks for certain tumor markers
  • Assesses neuroendocrine activity

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
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