What's this test for?

This test is ideal if you're experiencing signs linked to mild cystic fibrosis, unexplained pancreatitis, or lung issues like bronchiectasis that don't have a clear cause. It's also used for infertile men who have been diagnosed with congenital absence of the vas deferens (CBAVD), since this genetic feature is closely tied to CFTR gene changes. If you've already tested positive for the R117H CFTR variant, this test helps clarify how that finding may affect you.

What's included in this test?

This is a single, targeted genetic analysis rather than a multi-marker panel, so there isn't a list of separate biomarkers. It specifically looks at the poly-T tract in intron 8 of the CFTR gene, which affects how much functional CFTR protein your body produces. This detail matters because certain poly-T variants (like 5T) are strongly connected to CBAVD and mild cystic fibrosis symptoms in adults.

What happens after I get my results?

Your results will show up securely in your account along with an explanation of what the poly-T finding (5T, 7T, or 9T) means. If your result points to a form associated with CBAVD or mild CF-related symptoms, next steps often include discussing family planning options or further targeted gene testing, since this specific test does not measure TG tract length. A standard lab report is available to download from your account at any time, and you can track this result alongside any future related testing using the trends feature.

How can I naturally support respiratory and reproductive health?

While genetics can't be changed through lifestyle, supporting your overall lung and reproductive health can still help you feel your best. Staying well-hydrated, avoiding smoking or secondhand smoke, and getting regular light exercise all support lung function. Eating a balanced diet with enough zinc and antioxidants is also linked to better reproductive health in men.

When will I get my results?

Results for this specialized genetic test are typically ready within about 7 days of your sample being processed at the lab. Genetic tests like this one take a bit longer than routine bloodwork because of the detailed analysis involved. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

This test is a good fit for men who've been diagnosed with congenital absence of the vas deferens and are exploring the cause of their infertility. It's also useful for people with mild, unexplained CF-like symptoms such as chronic sinus issues, bronchiectasis, or repeated pancreatitis without another clear explanation. Additionally, anyone who has already tested positive for the R117H CFTR variant may need this test to better understand that result.

What symptoms indicate I may need this test?

Signs that may point to a need for this test include unexplained infertility in men, chronic respiratory infections or bronchiectasis without a known cause, and repeated bouts of pancreatitis that doctors can't otherwise explain. Some people are directed to this test after a partial CF carrier screen already flagged the R117H variant. These are subtler, milder presentations than classic childhood cystic fibrosis.

What is CFTR poly-T status and why does it matter?

The CFTR gene helps control the flow of salt and water in and out of cells, which matters most in the lungs, pancreas, and reproductive tract. The poly-T tract is a small stretch of DNA within this gene that can come in different lengths (5T, 7T, or 9T), and shorter versions like 5T reduce how much working CFTR protein gets made. This reduction is strongly linked to CBAVD and can contribute to milder CF-related symptoms in adults.

What does a 5T poly-T result mean?

A 5T result means you carry the shortest, least efficient version of this CFTR gene segment, which is associated with reduced CFTR protein production. In men, this is the variant most strongly linked to congenital absence of the vas deferens and resulting infertility. It can also raise the chance of having mild, CF-related symptoms, though many people with a 5T result have no symptoms at all.

What should I do if my results show a significant poly-T variant?

If your results show a 5T variant or another finding you weren't expecting, consider follow-up genetic counseling resources or additional targeted CFTR testing, such as TG tract length analysis, for a fuller picture. If infertility is the concern, this information can help guide conversations about family planning and reproductive options. Keeping a copy of your report handy for any future related testing is a smart step.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

CFTR Poly-T Test - Male Infertility & CF Gene Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]