What's this test for?

This test is ideal if you're worried about a strong family history of breast or stomach (gastric) cancer, especially if relatives were diagnosed at a young age or with a rare type called diffuse gastric cancer. It looks at the CDH1 gene to see if you carry a change that raises your lifetime risk for these cancers. Many people take this test after a genetic counselor or family history review suggests an inherited pattern may be at play.

What's included in this test?

This test includes full gene sequencing plus deletion/duplication analysis, which together catch both small letter-by-letter changes and larger missing or extra pieces of the CDH1 gene. Looking at both types of changes matters because either kind can turn off the gene's normal cancer-protective function. This dual approach gives a more complete picture than sequencing alone.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive, negative, or uncertain finding means for the CDH1 gene. If a mutation is found, next steps usually include closer cancer screening schedules and discussing risk-reducing options with a genetics specialist, while a negative result may simply mean continuing routine screening. You can download the full lab report from your account at any time, and because this is a one-time genetic result, tracking over time is less relevant than for markers that change, though you can keep the report for future reference or for family members.

How can I naturally support healthy cells and lower cancer risk?

While no lifestyle change can undo a genetic mutation, eating a diet rich in vegetables, fruits, and fiber while limiting processed and smoked foods may support overall stomach health. Avoiding tobacco and limiting alcohol are two of the most impactful habits for reducing cancer risk in general. Regular physical activity and maintaining a healthy weight also support your body's natural defenses, but these habits work alongside, not instead of, medical screening.

When will I get my results?

Results for this test are typically ready within about 7 days after your sample is processed at the lab. Genetic tests like this one take a bit longer than standard blood work because the lab has to carefully read through the entire gene sequence and check for larger structural changes. You'll receive a notification and can view your report as soon as it's ready in your account.

Who should consider this test?

This test is a good fit for people with a family history of breast cancer, diffuse gastric (stomach) cancer, or lobular breast cancer, particularly if these cancers appeared in multiple relatives or at a young age. It's also worth considering if a close relative has already tested positive for a CDH1 mutation. Individuals of any gender can carry and pass on this gene, so family history from both sides matters.

What symptoms indicate I may need this test?

CDH1-related conditions usually don't cause symptoms until cancer has already developed, so this test is more about family history than current symptoms. Warning signs that prompt testing include multiple family members with stomach or breast cancer, a relative diagnosed with diffuse gastric cancer, or breast cancer diagnosed before age 50. If you or a relative have had unexplained stomach pain, unintended weight loss, or early-onset breast lumps alongside a concerning family history, this test may offer useful answers.

What does it mean if a CDH1 mutation is found?

A positive result means you carry a change in the CDH1 gene that significantly raises your lifetime risk of diffuse gastric cancer and lobular breast cancer, though it does not mean you will definitely develop cancer. This finding typically leads to a discussion about enhanced screening, such as more frequent endoscopies or breast imaging, and in some cases preventive procedures. It's also useful information to share with blood relatives, since they may want to get tested too.

What does a negative CDH1 result mean?

A negative result means no CDH1 mutation was found, which is reassuring, but it doesn't rule out all cancer risk, especially if your family history is still strong. Some families have an inherited risk pattern caused by a gene that hasn't been identified yet. If your family history remains concerning, continuing standard cancer screening based on your personal risk factors is still a smart move.

How often should I retest?

CDH1 is a genetic test, so your result doesn't change over time and retesting the same gene isn't usually needed. However, if new genetic technology becomes available or your family history changes significantly, it may be worth revisiting genetic testing options. Family members who haven't been tested yet may want to consider testing based on your results.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

CDH1 Gene Test - Hereditary Breast & Gastric Cancer Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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