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CD45 IHC test for evaluating suspected lymphoma or blood cancer origin

CD45 Leukocyte Marker Test for Lymphoma Evaluation

CD45 (Leukocyte Common Antigen), IHC with Interpretation

  • Identify blood cell origin in tumors
  • Screen tissue for lymphoma indicators
  • Assess unusual masses or lymph nodes
$829
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you or someone in your care has a biopsy or tissue sample that needs to be evaluated for a possible blood-related cancer, like lymphoma. It helps pathologists figure out if abnormal cells found in a tumor came from blood-forming (hematopoietic) cells or from another type of tissue. This is usually ordered as a follow-up to imaging or an initial biopsy that found something concerning.

What's included in this test?

This is a single, specialized immunohistochemistry (IHC) stain rather than a panel of biomarkers, so there isn't a list of separate markers included. Instead, a tissue sample is stained with an antibody that targets CD45, a protein found on almost all blood-forming cell types, to see if the cells in question originated from the blood and immune system. This helps distinguish blood-related cancers, like lymphomas, from other types of tumors that started elsewhere in the body.

What happens after I get my results?

Your results will be available in your account along with an explanation of what the staining pattern means for your sample. Because this is a specialized tissue test rather than a simple numeric value, the report will describe whether the cells showed the expected staining pattern and what that suggests about the tissue type. You can download the full lab report from your account at any time, and if further testing or repeat biopsies are needed over time, you can track those results together using the trends feature. If results indicate something concerning, consider this a signal to pursue follow-up testing promptly.

How can I naturally support healthy immune and lymphatic function?
While this test itself is diagnostic and not something lifestyle changes can influence, supporting your overall immune health is always a good idea. Eating a balanced diet rich in fruits, vegetables, and lean protein, staying physically active, getting enough sleep, and managing stress all help your immune system function well. Avoiding tobacco and limiting alcohol also supports healthy blood and lymph tissue over time.
When will I get my results?
Results for this specialized tissue stain typically take about 7 days to process, since it involves careful lab preparation and interpretation by trained pathology staff. You'll see your results posted directly to your account once they're finalized. If your situation feels urgent, don't wait on results alone — seek medical care right away if you're experiencing severe or worsening symptoms.
Who should consider this test?
This test is typically considered when a biopsy or tissue sample has already shown an unusual growth or mass and there's a need to determine its cell type. It's especially relevant if there's a family history of lymphoma or blood cancers, or if imaging has revealed enlarged lymph nodes or an unexplained mass. It's a diagnostic tool used alongside other clinical findings, not a routine screening test for the general population.
What symptoms might lead someone to need this test?
Symptoms that might prompt this kind of tissue evaluation include unexplained lumps or swollen lymph nodes, unexplained weight loss, persistent fevers, drenching night sweats, or ongoing fatigue. These symptoms alone don't confirm anything, but combined with a suspicious mass on imaging or biopsy, they're often what leads to this type of testing. If you're experiencing these symptoms, getting a tissue sample evaluated can help clarify what's going on.
What is CD45 and why does it matter?
CD45 is a protein found on the surface of nearly all blood and immune system cells, including white blood cells, but not on platelets or red blood cells. By checking whether a tissue sample's cells carry this protein, pathologists can tell if a tumor started from blood-forming cells or from another tissue type, like skin, muscle, or organ tissue. This distinction is a key first step in properly classifying certain cancers.
What does a positive CD45 result mean?
A positive result means the cells being examined show the marker typically found on blood and immune cells, which points toward a blood-related origin, such as lymphoma or another hematopoietic condition. It doesn't diagnose a specific disease on its own — it's one piece of a larger puzzle that combines with other stains and clinical information. Additional specialized testing is usually needed to pinpoint the exact type of condition.
What should I do if my results are abnormal?
If your results show a positive or unexpected staining pattern, the next step is usually additional specialized testing to narrow down the exact type of cells involved. Keep a copy of your downloadable report handy, since it will be useful for coordinating any follow-up biopsies or tests. Don't panic — an abnormal result is a starting point for more answers, not a final diagnosis, but it's important to act on it promptly.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
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Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
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Demo results
CD45 (Leukocyte Common Antigen) Positive
Demo results
Negative Positive
Positive

What this means

A positive result means the examined tissue cells carry the CD45 marker, suggesting they originated from blood-forming (hematopoietic) cells rather than another tissue type. This finding supports further evaluation for conditions like lymphoma but is not a diagnosis on its own.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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CD45 Leukocyte Marker Test for Lymphoma Evaluation

  • Identify blood cell origin in tumors
  • Screen tissue for lymphoma indicators
  • Assess unusual masses or lymph nodes
$829
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.