What's this test for?

This test is ideal if you're being monitored for Acute Myeloid Leukemia (AML) and your care team wants to track a specific genetic change linked to this condition. It looks for the CBFB/MYH11 fusion, a marker that forms when parts of chromosome 16 rearrange (called inv(16) or t(16;16)). It's typically used after treatment to see if any disease is still present at a very low, hard-to-detect level.

What happens after I get my results?

Your results will appear in your online account with an explanation of what a positive or negative finding means for this specific marker. If the fusion transcript is still detected, retesting on a regular schedule is a common next step to track whether the level is rising, falling, or staying the same over time. If your result shows a concerning increase or you have new symptoms like fatigue, easy bruising, or fever, seek medical care right away. A downloadable lab report is always available, and you can track your results over time using the trends feature.

What symptoms indicate I may need this test?

This test is generally used for people already diagnosed with or treated for AML, not for screening based on everyday symptoms. That said, symptoms like unusual fatigue, frequent infections, easy bruising or bleeding, and unexplained weight loss are commonly linked to AML. If you've completed treatment, this test helps check whether the disease marker is still detectable, even if you feel well.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. This test uses a specialized real-time PCR method, which takes a bit longer than routine bloodwork because it precisely measures very small amounts of genetic material. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

This test is best suited for people who have been diagnosed with AML involving the inv(16) or t(16;16) chromosome change and are being monitored during or after treatment. It's also useful for tracking minimal residual disease (MRD), meaning very small amounts of leukemia cells that can remain after treatment appears successful. It is not intended as a general health or wellness screening test.

What is the CBFB/MYH11 fusion and why does it matter?

The CBFB/MYH11 fusion is an abnormal joining of two genes that happens when a piece of chromosome 16 flips and reattaches in the wrong spot. This genetic change is strongly linked to a specific subtype of Acute Myeloid Leukemia. Tracking this fusion over time helps show whether leukemia cells are still present in the body, even at levels too low to see under a microscope.

What does a positive result mean?

A positive result means the CBFB/MYH11 fusion transcript was detected in your sample, which can indicate that some leukemia cells are still present. The amount detected (quantitative level) matters just as much as whether it's present at all, since rising levels over successive tests can signal a higher chance of relapse. This finding should prompt a conversation about next steps and possibly more frequent monitoring or treatment adjustments, so seek medical care promptly if you receive this result.

What does a negative result mean?

A negative result means the fusion transcript was not detected at a level the test could measure, which is a reassuring sign that residual disease is very low or undetectable. It doesn't guarantee that all leukemia cells are gone, since extremely small amounts can sometimes fall below the test's detection limit. Continued monitoring on a regular schedule is still recommended even with a negative result.

How often should I retest?

Retesting frequency depends on your individual treatment history and how your levels have trended in previous tests, so there's no single fixed schedule for everyone. Many people monitoring for minimal residual disease retest every few months, especially in the first couple of years after treatment. Tracking your results over time using the trends feature can help you and your care team spot patterns early.

What should I do if my results are abnormal?

If your result comes back positive or shows a rising trend, don't panic, but do treat it as a signal to act quickly. Reach out for medical care as soon as possible so the finding can be put into context with your full treatment history and any other testing. In the meantime, keep track of any new symptoms like fatigue, fevers, or bruising, and keep your downloadable lab report handy to share as needed.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

CBFB/MYH11 PCR Test - AML Relapse Monitoring

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]