What's this test for?

This test is ideal if you're experiencing sudden confusion, memory problems, seizures, or muscle twitching and cramping that won't go away. It helps if you have unexplained nerve symptoms like muscle stiffness, spasms, or excessive sweating that started fairly quickly. The CASPR2 antibody test looks for a specific immune marker linked to rare autoimmune nerve and brain conditions.

What's included in this test?

This test measures CASPR2 antibodies, which the immune system mistakenly produces to attack proteins in nerve cells. When these antibodies are present, they can interfere with normal nerve and brain signaling, leading to the symptoms seen in limbic encephalitis and neuromyotonia. Identifying this marker helps explain unusual neurological symptoms that other tests may not catch.

What happens after I get my results?

Your results will show up in your account with an explanation of what a normal versus abnormal CASPR2 antibody level means. If your result is positive, prompt follow-up care is important since these conditions can progress quickly, so seek medical attention right away if you have severe symptoms like seizures or worsening confusion. A downloadable lab report is available in your account, and if you retest later on, you can track changes over time using the trends feature.

How can I naturally support nerve and immune health?

While this condition typically needs prompt medical attention, some general habits support nerve and immune function alongside proper care, like getting consistent sleep, eating an anti-inflammatory diet rich in omega-3s, and managing stress. Staying hydrated and avoiding alcohol or smoking can also help reduce nerve irritation. These steps are supportive only and are not a substitute for seeking care if you have severe or worsening symptoms.

When will I get my results?

Results for the CASPR2 antibody test are typically ready within about 7 days of your sample being received at the lab. You'll get a notification when your results are posted to your secure online account. Because this is a specialized antibody test, it takes a bit longer to process than routine bloodwork.

Who should consider this test?

This test is a good fit for people with sudden onset of memory loss, confusion, or seizures, as well as those with unexplained muscle twitching, cramping, or excessive sweating. It's also useful if you've had unexplained neurological symptoms that haven't been resolved by other testing. Consider this test if these symptoms came on relatively fast rather than gradually over years.

What symptoms indicate I may need this test?

Common symptoms include sudden confusion, short-term memory problems, seizures, hallucinations, or mood changes, along with muscle twitching, stiffness, cramps, or excessive sweating. Some people also experience trouble sleeping or unusual sensory symptoms like tingling or pain. If these symptoms appeared quickly over days to weeks, it's worth checking for this antibody marker.

What is CASPR2 and why does it matter?

CASPR2 is a protein found on nerve cells that helps them send signals properly. In some autoimmune conditions, the body mistakenly makes antibodies against CASPR2, disrupting normal nerve and brain function. Detecting these antibodies matters because it can explain otherwise puzzling neurological symptoms and point toward the right next steps for care.

What does a positive CASPR2 antibody result mean?

A positive result means your immune system is producing antibodies that attack CASPR2 proteins on nerve cells, which is associated with conditions like limbic encephalitis or neuromyotonia. This finding, combined with your symptoms, helps explain what's happening in your nervous system. Because these conditions can be serious, a positive result should prompt quick follow-up and, if symptoms are severe, urgent medical attention.

What should I do if my results are abnormal?

If your CASPR2 antibody test comes back positive, don't wait to address concerning symptoms like seizures, severe confusion, or rapidly worsening muscle problems — seek medical care right away in those cases. For milder or stable symptoms, use the detailed report in your account to understand your result and consider retesting or additional evaluation as advised. Keeping a symptom journal can also help track any changes over time.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

CASPR2 Antibody Test - Nerve & Brain Symptom Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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