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C1q antibody test for lupus patients monitoring kidney inflammation and disease flares

C1q Antibody Test for Lupus Kidney Monitoring

C1q Antibody (IgG)

  • Monitor lupus-related kidney inflammation levels
  • Detect early signs of kidney flares
  • Track disease activity over time
$480
First results as soon as overnight*

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Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're experiencing symptoms of a lupus flare, such as swelling in your legs, foamy or dark urine, high blood pressure, or unexplained fatigue, and you or your care history involves systemic lupus erythematosus (SLE). It helps check whether your kidneys may be affected by lupus, a condition called lupus nephritis. It's also useful if you've been previously diagnosed with lupus nephritis and want to track whether your disease activity is changing.

How should I prepare for this test?

How can I naturally support kidney health if I have lupus? Staying well-hydrated, reducing salt intake, and eating an anti-inflammatory diet rich in fruits, vegetables, and omega-3 fatty acids can help support kidney function. Regular, moderate exercise and stress management techniques like meditation may also help reduce overall inflammation. Avoiding NSAIDs when possible, since they can strain the kidneys, and getting adequate sleep are additional simple steps that support your body's ability to manage lupus-related inflammation.

What's included in this test?

This test measures one specific autoantibody that targets a protein called C1q, which plays a role in immune system regulation. This single marker matters because its presence and level are closely tied to active kidney inflammation in people with lupus, making it useful for spotting early signs of a flare before more damage occurs.

What happens after I get my results?
Your results will be available in your account, with each value's normal range clearly explained so you understand where you fall. If your C1q antibody level is elevated, next steps typically include closer monitoring of kidney function, watching for symptoms like swelling or changes in urination, and considering retesting within a few months to track any changes. A downloadable standard lab report is available directly from your account, and you can track your results over time using the trends feature to see whether your levels are rising, falling, or stable. If your result is very high alongside symptoms like severe swelling or blood in your urine, seek medical care promptly.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. Once ready, you'll be notified and can view them directly in your account. This turnaround gives you a relatively quick way to check on disease activity without a long wait.
Who should consider this test?
People who already have a lupus diagnosis and want to monitor kidney involvement should consider this test, especially if they've had lupus nephritis before. It's also worth considering if you're noticing new symptoms like leg swelling, foamy urine, or unexplained fatigue that could point to a kidney flare. Those working to catch disease flares early, before major kidney damage occurs, benefit most from regular monitoring with this test.
What symptoms indicate I may need this test?
Symptoms that suggest you might benefit from this test include swelling in your legs, ankles, or around your eyes, foamy or dark-colored urine, unexplained high blood pressure, and persistent fatigue. These can be signs that lupus is affecting your kidneys. If you have a known lupus diagnosis and notice any of these changes, this test can help clarify whether a kidney flare is happening.
What is C1q antibody and why does it matter?
C1q antibody is a protein your immune system sometimes produces that attacks a normal part of your body's defense system called C1q. In people with lupus, having this antibody in the blood is closely linked to active inflammation in the kidneys. It matters because rising levels can appear before a kidney flare becomes severe, giving you a chance to act early.
What does a high C1q antibody result mean?
A high result suggests there may be active inflammation happening in your kidneys related to lupus, sometimes called lupus nephritis. This doesn't automatically mean permanent damage, but it's a signal to pay closer attention to kidney-related symptoms like swelling or urine changes. Retesting and closely monitoring symptoms in the following weeks is a reasonable next step, and if you notice significant swelling or reduced urination, seek medical care right away.
How often should I retest?
If you have a history of lupus nephritis or fluctuating disease activity, retesting every few months is often useful to catch changes early. If your levels are currently normal and you're feeling well, testing less frequently, such as every 6 months, may be reasonable. Anytime you notice new symptoms like swelling or urine changes, it's a good idea to retest sooner rather than waiting for your next scheduled check.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
C1q Antibody (IgG) 18 U/mL
Demo results
Negative (<10 U/mL) Positive (≥10 U/mL)
18 U/mL

What this means

This result is above the negative threshold, suggesting antibodies against C1q are present in your blood. In someone with lupus, this often correlates with active kidney inflammation, also called lupus nephritis. It's a signal to watch for symptoms like swelling or changes in urination and consider follow-up testing.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
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C1q Antibody Test for Lupus Kidney Monitoring

  • Monitor lupus-related kidney inflammation levels
  • Detect early signs of kidney flares
  • Track disease activity over time
$480
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.