What's this test for?

This test is ideal if you're being evaluated for or already diagnosed with certain cancers, such as gastrointestinal stromal tumors (GIST), certain types of leukemia, or systemic mastocytosis. It looks for specific changes in the c-KIT gene that can affect how a cancer behaves and how it may respond to certain treatments. It's typically used as part of a broader cancer workup rather than as a general screening test.

What's included in this test?

This test analyzes specific regions of the c-KIT gene, called exons, that are known hot spots for mutations linked to cancer. Checking these exons matters because different mutation locations are tied to different cancers and can affect prognosis and treatment response. Rather than a general panel, this is a focused, cell-based genetic analysis targeting these known trouble spots.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative mutation finding means. Because this is a specialized genetic test tied to specific cancer types, next steps usually involve discussing the finding with your cancer care team so it can be factored into treatment planning. You can download a standard lab report from your account at any time, and if repeat testing is ever needed, you'll be able to track results over time using the trends feature.

Who should consider this test?

This test is generally considered for people who have already been diagnosed with, or are strongly suspected of having, a condition like GIST, certain acute leukemias, or systemic mastocytosis. It's most useful when a cancer care team wants more detail on the tumor's genetic makeup to guide treatment decisions. It's not typically used as a routine screening test for people without symptoms or a prior diagnosis.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. This test involves detailed genetic analysis, so it takes a bit longer than routine bloodwork. You'll be notified as soon as your results are available in your account.

What symptoms indicate I may need this test?

On its own, c-KIT mutation testing isn't ordered based on everyday symptoms like fatigue or pain. It's usually ordered after imaging or biopsy has already suggested a tumor, such as a mass found in the digestive tract that may be GIST, or after a leukemia or mastocytosis diagnosis is being worked up. If you've been told a growth or blood cancer needs genetic characterization, this is the type of test that would apply.

What is a c-KIT mutation and why does it matter?

c-KIT is a gene that normally helps control cell growth. When it mutates, or changes, it can get stuck in the 'on' position and cause cells to grow out of control, which is how certain cancers form. Knowing whether a tumor has one of these mutations, and exactly where the mutation is located, helps explain how aggressive the cancer might be and whether targeted therapies are likely to work.

What does a positive c-KIT mutation result mean?

A positive result means a mutation was found in one of the tested c-KIT exons, which can be associated with a higher relapse rate or more aggressive disease course depending on which exon is involved. It also often means certain targeted cancer drugs may be an option, since some treatments are designed specifically to work against c-KIT-driven cancers. This finding is usually reviewed alongside your other test results and imaging as part of your overall treatment plan.

What does a negative c-KIT mutation result mean?

A negative result means none of the specific c-KIT exon mutations tested were detected in your sample. This doesn't rule out cancer, but it does mean this particular genetic pathway isn't likely driving the disease, which can shift which treatment options are considered. Additional genetic or molecular testing may still be recommended depending on your specific diagnosis.

How often should I retest?

c-KIT mutation status is usually checked once at diagnosis rather than on a regular schedule, since it reflects the genetic makeup of the tumor at that point in time. Retesting might be considered if a new tumor sample becomes available, such as after surgery or if the cancer changes or returns. Your cancer care team will guide the timing if repeat testing becomes relevant.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

c-KIT Mutation Analysis - GIST & Leukemia Testing

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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