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BRAF V600E Mutation Test (IHC) for Tumor Tissue
BRAF V600E Mutation, IHC without Interpretation
3,599 reviews
Detect key tumor mutation status accurately
Screen melanoma and thyroid cancer markers
Assess tumor genetics for treatment planning
$632
CLIA-certified labs
First results as soon as overnight*
All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified
Prescription & all lab fees included
Go directly to the lab, no extra fees
Doctor's guidance included
Easy to understand results
Fast & convenient
Lab visit as quick as 10 mins in & out
Many results come back overnight *
90-day money back guarantee
Save time & skip the doctor’s office
Lab visit as quick as 10 minutes
Results explained, with clear next steps
LegitScript certified
No questions asked refunds
The price you see is the price you pay
Many results come back overnight *
90-day money back guarantee
Save time & skip the doctor’s office
Lab visit as quick as 10 minutes
Results explained, with clear next steps
LegitScript certified
No questions asked refunds
The price you see is the price you pay
What's this test for?
This test is ideal if you or someone treating you needs to know whether a tumor sample carries the BRAF V600E mutation. It's commonly used after a diagnosis of melanoma, papillary thyroid carcinoma, colorectal carcinoma, ovarian serous carcinoma, or hairy cell leukemia to help understand the specific characteristics of the cancer. Knowing this mutation status can be an important piece of information when thinking through treatment options.
What's included in this test?
This is a single, targeted test that uses immunohistochemistry (IHC) to detect the BRAF V600E mutated protein directly in a tissue sample. It doesn't include an interpretation from a pathologist beyond the raw IHC result, so it's meant for someone who wants the mutation status itself. This focused approach is useful when you already know which mutation you're checking for.
What happens after I get my results?
Your results will be available in your account, along with an explanation of what the finding means. Next steps depend on the result: a positive finding may open the door to targeted therapy discussions, while a negative finding means this particular mutation isn't driving the tumor. You can download the standard lab report directly from your account at any time, and if repeat testing is ever needed, you'll be able to track results over time using the trends feature.
How can I naturally support my body during cancer testing and treatment?
While no lifestyle change can affect a tumor's mutation status, supporting your overall health can help you feel your best during this process. Eating a balanced diet rich in fruits, vegetables, and lean protein, staying physically active as tolerated, getting enough sleep, and managing stress through activities like walking or meditation can all help your body cope. These steps work alongside, not instead of, any treatment path you pursue.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. Because this involves specialized tissue analysis, turnaround can occasionally vary slightly depending on sample complexity. You'll be notified as soon as your results are posted to your account.
Who should consider this test?
This test is a good fit for anyone with a confirmed tumor diagnosis in melanoma, thyroid, colorectal, ovarian, or certain blood cancers who wants to know if the BRAF V600E mutation is present. It's often considered as part of understanding tumor biology after a biopsy or surgical sample has been obtained. If you've been told your cancer type commonly carries this mutation, this test can confirm whether it applies to you specifically.
What symptoms indicate I may need this test?
This test isn't ordered based on symptoms directly, since it requires an existing tissue sample from a diagnosed tumor. If you've already been diagnosed with melanoma, thyroid cancer, colorectal cancer, ovarian cancer, or hairy cell leukemia, this test can add useful detail to what's already known about the tumor. It's typically a follow-up step after imaging, biopsy, or surgery has identified a mass or lesion.
What is the BRAF V600E mutation and why does it matter?
BRAF is a gene that normally helps control cell growth, but when it develops the V600E mutation, it can cause cells to grow and divide uncontrollably, contributing to tumor formation. This specific mutation shows up most often in melanoma, papillary thyroid carcinoma, colorectal carcinoma, ovarian serous carcinoma, and hairy cell leukemia. Knowing whether a tumor has this mutation matters because it's a well-studied marker that can shape how a cancer is understood and managed.
What does a positive BRAF V600E result mean?
A positive result means the mutated protein was detected in the tissue sample, indicating the tumor's cells carry this specific genetic change. This is common in the cancer types mentioned above and is considered useful information about how the tumor is behaving. It's a good idea to discuss what this means for your specific situation with whoever is managing your care plan.
What should I do if my results are abnormal?
If your result comes back positive for the BRAF V600E mutation, keep a copy of your lab report and share it with whoever is coordinating your cancer care, since this information is often used alongside other test results. There's no lifestyle fix for a mutation, but staying on top of follow-up appointments and additional testing your care plan calls for is the most useful next step. If you experience any sudden, severe symptoms related to your condition, seek medical care right away.
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Demo results
BRAF V600E Mutation (IHC)Negative
Demo results
NegativePositive
Negative
What this means
A negative result means the BRAF V600E mutated protein was not detected in the tumor tissue sample. This suggests the tumor is not being driven by this particular genetic change. A positive result would mean the mutation was detected, which can be relevant information for understanding the tumor's behavior.
Recommended actions
Keep a copy of your lab report for your records
Share results with whoever coordinates your ongoing cancer care
Discuss additional tumor marker testing if recommended
Continue with your existing treatment and monitoring plan
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
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