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BRAF V600E mutation test for patients with melanoma, thyroid, or colorectal cancer concerns

BRAF V600E Mutation Test — Tumor Genetic Marker Panel

BRAF V600E Mutation, IHC with Interpretation

  • Detect key tumor genetic mutation
  • Screen melanoma and thyroid cancer risk
  • Assess targeted treatment options available
$834
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being evaluated for a tumor or cancer diagnosis and need more information about how it might behave or respond to treatment. It looks for a specific genetic change called the BRAF V600E mutation, which is found in cancers like melanoma, thyroid cancer, colorectal cancer, ovarian cancer, and a type of blood cancer called hairy cell leukemia. This test is typically used alongside other diagnostic tools as part of a broader cancer workup.

What's included in this test?

This test uses a lab technique called immunohistochemistry (IHC) to check tumor tissue for the BRAF V600E protein, a marker of a specific gene mutation. Finding this mutation matters because it can affect how aggressive a cancer is and whether it will respond to certain targeted drug therapies. A trained pathologist interprets the stained tissue sample and provides a written interpretation with your results.

What happens after I get my results?

Your results will be available in your account, with a clear explanation of what a positive or negative finding means. If the mutation is detected, the next step is usually further testing or treatment planning, since certain targeted therapies work specifically on tumors with this mutation. A standard lab report with the pathologist's interpretation is downloadable from your account, and you can keep records over time using the trends feature. Because this result can carry serious implications, review it carefully and act quickly on any recommended next steps.

How can I naturally support my body during cancer treatment?
While no natural remedy can treat a BRAF mutation, supporting your body with good nutrition, adequate sleep, and light physical activity can help you tolerate treatment better. Eating a variety of colorful vegetables, lean proteins, and whole grains supports your immune system during this time. Managing stress through mindfulness or gentle movement like walking or yoga may also help your overall well-being. These steps are supportive, not a substitute for appropriate cancer care.
When will I get my results?
Results are typically ready within about 7 days of your sample being processed at the lab. This timeframe allows the pathologist to carefully prepare and examine the tissue sample using the immunohistochemistry staining process. You'll receive a notification as soon as your results are available in your account.
Who should consider this test?
This test is a good option for anyone recently diagnosed with melanoma, papillary thyroid carcinoma, colorectal carcinoma, ovarian serous carcinoma, or hairy cell leukemia who wants more detail about their tumor's genetic makeup. It's also useful if you're exploring targeted treatment options, since some therapies only work on tumors with this specific mutation. This test requires a tissue sample, so it's typically ordered following a biopsy or surgical removal of tumor tissue.
What symptoms indicate I may need this test?
There aren't specific symptoms tied directly to a BRAF mutation itself — instead, this test is usually recommended after a tumor has already been identified through imaging, biopsy, or surgery. Symptoms that lead to that initial diagnosis vary widely depending on the cancer type, ranging from a changing mole (melanoma) to a lump in the neck (thyroid cancer) or changes in bowel habits (colorectal cancer). If you've noticed any of these changes, the first step is getting evaluated so a tissue sample can be collected.
What does a positive BRAF V600E result mean?
A positive result means the tumor cells carry this specific genetic change, which can make the cancer behave more aggressively in some cases. On the flip side, a positive result also opens the door to targeted therapies designed specifically to block the effects of this mutation. Your written interpretation will explain what this means for your particular tumor type.
What does a negative BRAF V600E result mean?
A negative result means this specific mutation was not detected in the tissue sample tested. This doesn't rule out cancer or other mutations — it simply means BRAF-targeted therapies are less likely to be effective for your tumor. Other genetic or molecular tests may still be useful to fully understand your tumor's characteristics.
What should I do if my results are abnormal?
If your result shows the BRAF V600E mutation is present, use this information to explore targeted treatment options designed for BRAF-positive tumors. Keep a copy of your lab report handy, as this information is often needed when planning cancer treatment. If you're experiencing worsening symptoms or have urgent concerns, seek medical care right away rather than waiting.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
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Fast & confidential, we never sell or share your data
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Demo results
BRAF V600E Mutation (IHC) Negative
Demo results
Negative Positive
Negative

What this means

A negative result means the BRAF V600E mutation was not detected in the tumor tissue sample tested. This suggests BRAF-targeted therapies are unlikely to be effective for this particular tumor. Other molecular tests may be needed to fully characterize the tumor's genetic profile.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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BRAF V600E Mutation Test — Tumor Genetic Marker Panel

  • Detect key tumor genetic mutation
  • Screen melanoma and thyroid cancer risk
  • Assess targeted treatment options available
$834
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.