What's this test for?

This test is ideal if you're concerned about your risk for coronary heart disease, especially if you have a family history of heart attacks, blood clots, or clotting disorders. It looks at a specific genetic change that can raise the level of fibrinogen, a protein involved in blood clotting, in your blood. Knowing your genetic status can help you and your family understand inherited heart disease risk and take early action.

What's included in this test?

This test looks specifically at one genetic marker in the fibrinogen gene that has been linked to higher fibrinogen levels in the blood. Fibrinogen plays a key role in blood clotting, and elevated levels are considered an independent risk factor for coronary heart disease, so understanding this genetic marker helps clarify part of your overall cardiovascular risk picture.

What happens after I get my results?

Your results will show up in your account along with an explanation of what a positive or negative finding means. If your test shows the gene variant, practical next steps include focusing on heart-healthy habits like regular exercise, a lower-sodium diet, and not smoking, since these help manage fibrinogen and clotting risk. The full lab report is available to download from your account at any time, and since this is a one-time genetic result, tracking over time is mainly useful for monitoring related markers like cholesterol or blood pressure rather than retesting this specific gene.

How can I naturally support healthy fibrinogen levels?

Regular aerobic exercise, like brisk walking or cycling several times a week, has been shown to help lower fibrinogen levels naturally. Eating a diet rich in omega-3 fatty acids from fish, walnuts, or flaxseed, cutting back on processed foods, and quitting smoking can also make a meaningful difference. Managing stress through sleep and relaxation techniques supports healthy clotting balance as well.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. You'll receive a notification once they're available, and you can log into your account to view the full report at that time.

Who should consider this test?

This test is worth considering if you have a family history of early heart disease, blood clots, or stroke, or if you already know fibrinogen runs high in your family. It's also useful for people who want a clearer picture of their inherited cardiovascular risk factors beyond standard cholesterol testing.

What symptoms indicate I may need this test?

Since this is a genetic test, it isn't tied to specific day-to-day symptoms, but a strong family history of heart attacks, blood clots, or unexplained clotting problems is a good reason to consider it. If close relatives have had early coronary heart disease, that's a signal this test might give useful information.

What is the -455G→A fibrinogen mutation and why does it matter?

This is a small change in the DNA sequence located in the control region of the fibrinogen gene, which affects how much fibrinogen protein your body produces. People who carry this variant tend to have higher fibrinogen levels, and since fibrinogen is involved in clot formation, higher levels are linked to a greater independent risk of coronary heart disease. Knowing you carry this variant can motivate closer attention to other heart-healthy habits.

What does a positive result mean?

A positive result means you carry the genetic variant associated with higher fibrinogen levels and a somewhat increased independent risk for coronary heart disease. It does not mean you will definitely develop heart disease, but it's useful information to combine with other risk factors like cholesterol, blood pressure, and lifestyle. Many people with this variant lower their overall risk through diet, exercise, and not smoking.

What should I do if my results are positive?

If your result is positive, focus on the cardiovascular risk factors you can control: eat a heart-healthy diet, stay physically active, avoid smoking, and manage stress and sleep. It's also a good idea to keep track of related markers like cholesterol and blood pressure over time using the trends feature in your account. If you ever experience symptoms like chest pain, sudden leg swelling, or shortness of breath, seek medical care right away.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Fibrinogen Gene Mutation Test - Heart Disease Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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