What's this test for?

This test is ideal if you're being evaluated for a suspicious tissue growth and your care team needs to tell whether it's benign or cancerous. It's often used when there's concern about mesothelioma, uveal melanoma, or an atypical Spitz tumor. The test looks at a tissue sample to help clarify a diagnosis that can be hard to pin down with standard tissue exams alone.

What's included in this test?

This test uses a lab technique called immunohistochemistry (IHC) to check whether a protein called BAP1 is present or missing in your tissue sample. Losing BAP1 expression is a pattern seen in certain cancers, so checking for it helps pathologists tell the difference between a harmless growth and a more serious one. A written interpretation from a pathologist is included to help make sense of the finding.

What happens after I get my results?

Your results will appear in your account along with an explanation of what the finding means for the tissue sample tested. Next steps depend on the result: a loss of BAP1 expression points toward a specific diagnosis and may lead to further testing or closer monitoring, while a normal result may lower suspicion for certain cancers. You can download the full lab report directly from your account at any time, and if repeat testing is ever needed, you can track results over time using the trends feature. If your report includes any values described as urgent, seek medical care right away.

How can I naturally support healthy cell function?

While no lifestyle change can reverse a genetic change like BAP1 loss, general habits that support healthy cells include eating a diet rich in vegetables and antioxidants, avoiding tobacco, limiting excess sun and UV exposure, and managing stress well. Regular exercise and good sleep also support your body's natural cell-repair processes. These habits won't replace medical follow-up but can support your overall health while you await results.

When will I get my results?

Results are typically ready within about 7 days after your tissue sample is processed at the lab. This turnaround allows time for the specialized staining and pathologist interpretation that this test requires. You'll receive a notification as soon as your report is available in your account.

Who should consider this test?

This test is a good fit for people who have had a biopsy of a suspicious growth — especially one suspected to be mesothelioma, a Spitz-type skin lesion, or a uveal (eye) melanoma — and need extra clarity beyond a routine tissue exam. It's also useful for people with a personal or family history of BAP1-related tumor syndrome. This test is a good next step when your biopsy findings alone aren't conclusive.

What symptoms indicate I may need this test?

You might consider this test if you have an unusual, changing, or fast-growing skin lesion, a persistent chest or abdominal mass, or vision changes linked to a suspicious eye growth. Unexplained symptoms like persistent chest pain, shortness of breath, or fluid buildup around the lungs can also prompt this kind of testing when mesothelioma is suspected. Any biopsy result that comes back unclear or atypical is another common reason this test gets ordered.

What does a loss of BAP1 expression mean?

When BAP1 expression is lost in a tissue sample, it means the cells are missing a protein that normally helps control cell growth and repair DNA damage. This pattern is commonly seen in malignant mesothelioma, uveal melanoma, and some atypical Spitz tumors, so it raises suspicion for one of these conditions. Losing BAP1 does not confirm cancer on its own — the pathologist interprets it alongside the rest of your tissue findings.

What causes loss of BAP1 expression?

BAP1 loss can happen because of an inherited genetic mutation passed down in families (BAP1 tumor predisposition syndrome) or because of a mutation that occurs only in the tumor cells themselves, unrelated to family history. Environmental exposures like asbestos are strongly linked to BAP1 loss in mesothelioma cases specifically. Genetic counseling can help clarify whether an inherited cause is involved.

What should I do if my results show BAP1 loss?

If your report shows a loss of BAP1 expression, the most important step is discussing the finding with your care team so it can be viewed alongside your full clinical picture. This finding often supports a specific diagnosis and may lead to additional imaging, staging tests, or genetic counseling if a hereditary link is suspected. Keeping a copy of your report and tracking any follow-up testing over time can help keep your care organized.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

BAP1 IHC Test - Mesothelioma & Melanoma Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

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