What's this test for?

This test is ideal if you're being monitored for a B-cell related blood cancer, such as a lymphoma or leukemia, or if you have a prior diagnosis and need to check for returning disease. It helps identify whether B-cells in your body are growing from a single abnormal clone, which is a sign of a B-cell neoplasm. It's also used to track minimal residual disease after treatment to see if the abnormal cells are still present at very low levels.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a clonal versus non-clonal finding means. Next steps depend on your specific situation: a positive finding may call for follow-up testing with a companion assay to reduce false negatives, while a negative result may still warrant retesting if symptoms persist. The full lab report can be downloaded from your account at any time, and if you test again in the future, you can track results side by side using the trends feature. If a result suggests active disease, seek follow-up care promptly.

What is B-cell clonality and why does it matter?

B-cells are immune cells that normally grow in a diverse mix to fight different infections. When one B-cell population grows out of control and dominates, it's called a clonal population, which is a hallmark of B-cell cancers like lymphoma or leukemia. Finding this pattern early helps confirm a diagnosis or catch a cancer coming back after treatment.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. This test uses a specialized PCR method, so it takes a bit longer than routine bloodwork. You'll get a notification as soon as your report is available in your account.

Who should consider this test?

This test is best suited for people with a suspected or confirmed B-cell neoplasm, such as certain lymphomas or leukemias, who need help confirming a diagnosis. It's also useful for people already treated for one of these conditions who want to check for minimal residual disease or early signs of relapse. It is not a general cancer screening test for people without prior findings or symptoms.

What symptoms indicate I may need this test?

Signs that might prompt this kind of testing include unexplained swollen lymph nodes, persistent fatigue, unexplained weight loss, night sweats, or abnormal results on a prior blood or bone marrow biopsy. If you've already been diagnosed with a B-cell cancer, changes in these symptoms after treatment can also be a reason to retest. These symptoms have many possible causes, so this test is typically used alongside other clinical findings.

What does a positive (clonal) result mean?

A positive or clonal result means the lab found evidence that one B-cell population has multiplied and become dominant, which is associated with B-cell cancers. Because this specific test can miss some cases, a positive finding is often confirmed alongside a companion test like the IGK assay to lower the chance of a false negative. This result is a signal to follow up quickly for additional workup and treatment planning.

What does a negative result mean?

A negative result means no dominant clonal B-cell population was detected in your sample. However, this test can miss up to 10-20% of true B-cell cancers, especially certain follicular lymphomas, plasma cell disorders, or B-lymphoblastic leukemias, so a negative result doesn't fully rule out disease if symptoms continue. Combining this test with the IGK assay improves detection accuracy.

How often should I retest?

Retesting frequency depends on your individual history and prior treatment for a B-cell neoplasm, so there's no single schedule that fits everyone. Many people monitoring for minimal residual disease retest periodically, such as every few months, to track whether abnormal cells reappear. Use the trends feature in your account to compare results over time and watch for changes.

What should I do if my results are abnormal?

If your result shows a clonal B-cell population, it's important to seek prompt follow-up care, especially if you're experiencing symptoms like swollen lymph nodes, fevers, or weight loss. Keep a copy of your downloadable lab report handy for any follow-up appointments or additional testing. Consider pairing this result with a companion test like IGK to get a fuller picture, and use the trends feature to monitor changes if you retest in the future.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

B-Cell Clonality Test - Lymphoma & Leukemia Monitoring

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]