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B-cell clonality PCR test for lymphoma diagnosis and residual disease monitoring

B-cell Clonality Panel (IGH, IGK) PCR Test

B-cell Clonality Panel (IGH, IGK), PCR

  • Detect abnormal B-cell lymphoma patterns
  • Monitor cancer recurrence after treatment
  • Screen swollen lymph node causes
$3141
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being evaluated for a possible B-cell lymphoid cancer or if you've already been diagnosed with one and need to check whether it's still active in your body. It looks at the DNA of your immune cells to see if a single abnormal cell line has multiplied out of control, which is a hallmark of B-cell lymphoma or leukemia. It's also useful for people in remission who want to check for early signs the disease is coming back.

How should I prepare for this test?

How can you naturally support your immune system while going through this testing process? Getting enough sleep, eating a balanced diet rich in fruits and vegetables, staying hydrated, and managing stress can all help your immune system function well. These habits won't change the test result itself, but they support your overall health while you wait for answers and during any follow-up care.

What's included in this test?

This panel checks two areas of your immune cell DNA — the genes that control antibody production — to see if one cell type has copied itself abnormally, which points to a possible B-cell cancer. Looking at both areas together catches far more cases than checking just one, giving a much more complete and reliable picture of clonality.

What happens after I get my results?
Your results will show up in your account along with an explanation of what a normal versus abnormal (clonal) pattern looks like. If the result is positive for clonality, the report will outline what that typically means and why prompt follow-up care is important, especially if you have symptoms like swollen lymph nodes or unexplained fatigue. You can download a standard lab report anytime from your account, and if you retest in the future, the trends feature lets you track results side by side over time.
When will I get my results?
Results from this test typically take about 7 days to process because it involves detailed DNA analysis in the lab. You'll get a notification as soon as your results are ready to view in your account. This turnaround time is standard for specialized molecular tests like this one, which require more time than routine blood work.
Who should consider this test?
This test is a good fit for people who have suspicious symptoms such as persistent swollen lymph nodes, unexplained weight loss, or night sweats that haven't gone away. It's also appropriate for people already diagnosed with a B-cell lymphoma or leukemia who need to monitor for minimal residual disease or check if the cancer has come back after treatment. People with an unclear diagnosis from other tests may also benefit from this more detailed molecular analysis.
What symptoms indicate I may need this test?
Common warning signs include lymph nodes that stay swollen for weeks without an obvious cause, ongoing fatigue that doesn't improve with rest, unexplained fevers or night sweats, and unintended weight loss. Some people also notice frequent infections or a general feeling of being unwell for an extended period. If you're experiencing several of these symptoms together, this test can help clarify what's going on at a cellular level.
What is B-cell clonality and why does it matter?
Normally, your body makes many different B-cells, each producing a slightly different antibody to fight off different germs. Clonality means one single B-cell has multiplied into a large group of identical copies, which is not normal and is a key sign of a B-cell cancer like lymphoma or leukemia. Detecting this pattern early helps confirm a diagnosis or catch a relapse before it progresses further.
How often should I retest?
If you've been diagnosed with a B-cell lymphoid cancer, retesting frequency depends on your treatment plan and how your condition is being tracked over time — many people retest every few months during active monitoring. If you're in remission, periodic retesting can help catch early recurrence before symptoms return. Your care team's monitoring schedule, if you have one, along with any new symptoms should guide how often you retest.
What should I do if my results are abnormal?
An abnormal (clonal) result means the lab found a pattern consistent with a B-cell cancer, and this needs prompt attention rather than a wait-and-see approach. Seek medical care quickly to discuss next steps, which may include imaging, a biopsy, or starting treatment depending on your specific situation. Keep a copy of your report handy since it contains details that will be useful for any follow-up care you pursue.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
B-cell Clonality (IGH/IGK Gene Rearrangement) Negative
Demo results
Negative (Polyclonal) Positive (Clonal)
Negative

What this means

A negative result means your B-cells show a normal, diverse pattern with no single cell line taking over, which is reassuring and does not support a B-cell lymphoid cancer. A positive result would mean one B-cell type has copied itself abnormally, a pattern often seen in B-cell lymphoma or leukemia.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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B-cell Clonality Panel (IGH, IGK) PCR Test

  • Detect abnormal B-cell lymphoma patterns
  • Monitor cancer recurrence after treatment
  • Screen swollen lymph node causes
$3141
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.