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ANCA autoimmune screening for patients with vasculitis or inflammatory bowel symptoms

ANCA Antibody Blood Test for Autoimmune Screening

ANCA Screen with MPO and PR3, with Reflex to ANCA Titer

  • Screen for autoimmune blood vessel disease
  • Detect antibodies linked to inflammation
  • Assess unexplained joint and organ symptoms
$746
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained symptoms like joint pain, persistent sinus or lung issues, blood in your urine, chronic digestive problems, or unusual fatigue that hasn't gone away. These can sometimes point to autoimmune conditions where the body's immune system mistakenly attacks its own tissues, including blood vessels or the gut lining. This screen helps identify antibodies linked to these conditions so you can understand what might be causing your symptoms.

What's included in this test?

This screen looks for two main types of antibodies, P-ANCA and C-ANCA, along with specific markers called MPO and PR3 that help pinpoint what type of autoimmune activity might be happening. If the initial screen comes back positive, the test automatically runs a follow-up titer to measure how much antibody is present, giving a clearer picture of disease activity. Together, these markers help identify autoimmune conditions affecting blood vessels, the gut, or other organs.

What happens after I get my results?

Your results will show up in your account with each value's normal range clearly explained so you know exactly where you stand. If your results come back positive or unclear, next steps typically involve additional testing or monitoring symptoms closely, and if you have severe symptoms like difficulty breathing or major swelling, you should seek medical care right away. You can download the standard lab report directly from your account at any time, and if you retest in the future, the trends feature lets you track changes over time.

How can I naturally support immune system balance?
While autoimmune antibody levels aren't something you can directly control through lifestyle alone, supporting your immune system with a balanced diet rich in anti-inflammatory foods like leafy greens, fatty fish, and berries can help. Getting consistent sleep, managing stress through activities like walking or meditation, and avoiding smoking can also reduce overall inflammation in your body. These habits won't replace testing but can support your overall health while you monitor your results.
When will I get my results?
Results are typically ready within about 7 days after your sample is collected at the lab. If the initial screen is positive, the added titer test may take a bit longer since it runs as a reflex test to measure antibody levels more precisely. You'll get a notification as soon as your results are ready to view in your account.
Who should consider this test?
This test is a good fit for people with symptoms like unexplained joint or muscle pain, chronic sinus problems, blood in the urine, persistent digestive issues, or ongoing fatigue that hasn't been explained by other causes. It's also useful for anyone who has been told they might have an autoimmune condition affecting blood vessels or organs and wants clarity before pursuing further evaluation. People with a family history of autoimmune diseases may also want to consider this screening.
What symptoms indicate I may need this test?
Common symptoms linked to the conditions this test screens for include joint pain, skin rashes, numbness or tingling, blood in urine, chronic sinus or lung problems, and unexplained weight loss. Digestive symptoms like ongoing diarrhea, abdominal pain, or blood in stool can also be signs worth investigating. If you're dealing with several of these symptoms at once without a clear cause, this screening can help narrow down what's going on.
What does a positive ANCA result mean?
A positive result means antibodies were detected that are associated with autoimmune conditions affecting blood vessels or organs like the kidneys and lungs. This doesn't automatically mean you have a specific disease, but it's a signal that further evaluation is worthwhile, especially if paired with symptoms. The titer level that follows a positive screen shows how much antibody is present, which can help gauge how active the condition may be.
How often should I retest?
If your first result comes back negative and you're not experiencing symptoms, you likely don't need to retest unless new symptoms develop. If you've had a positive result or are being monitored for a known condition, retesting every few months can help track whether antibody levels are rising, falling, or staying stable. Your results being tracked over time can help you and anyone reviewing your case spot meaningful trends.
What should I do if my results are abnormal?
If your results are outside the normal range, start by reviewing the detailed explanation included with your report to understand what the specific antibodies mean. Keep track of any symptoms you're having and consider retesting in a few months to see if levels change. If you experience severe or worsening symptoms like difficulty breathing, significant swelling, or blood in urine, seek medical care right away rather than waiting for a scheduled retest.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
ANCA (MPO/PR3 Antibodies) Negative
Demo results
Negative (Normal) Positive (Abnormal)
Negative

What this means

A negative result means no significant anti-neutrophil cytoplasmic antibodies were found in your blood, which is the expected, normal finding. This makes autoimmune vasculitis or related conditions less likely to be the cause of your symptoms. If symptoms continue, other causes may need to be explored.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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ANCA Antibody Blood Test for Autoimmune Screening

  • Screen for autoimmune blood vessel disease
  • Detect antibodies linked to inflammation
  • Assess unexplained joint and organ symptoms
$746
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.