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ANA screening panel for adults with joint pain, skin changes, or autoimmune concerns

ANA Screen with Reflex Testing for Autoimmune Symptoms

ANA Screen,IFA, with Reflex to Titer and Pattern/Systemic Sclerosis Panel 1

  • Screen for autoimmune warning signs
  • Check joint pain and skin changes
  • Detect early systemic sclerosis symptoms
$338
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing joint pain, skin thickening or tightening, unexplained fatigue, or Raynaud's-like symptoms (fingers turning white or blue in the cold) that could point to an autoimmune condition like systemic sclerosis. It's also useful if you have a family history of autoimmune disease and want to check for early warning signs. This panel helps identify whether your immune system is producing antibodies that attack your own tissues.

What's included in this test?

This panel starts with a screening test that looks for antinuclear antibodies, which are markers that show up when the immune system may be attacking the body's own cells. If that screen comes back positive, three additional specific antibodies are automatically tested to help narrow down whether the pattern is consistent with systemic sclerosis and which type it might be.

What happens after I get my results?

Your results will appear in your account with each value's normal range clearly explained, including whether your ANA screen was positive or negative and, if positive, the results of the reflex antibody tests. If your results are positive, next steps typically include tracking your symptoms and considering follow-up testing, since a positive result on its own doesn't confirm a diagnosis. A downloadable standard lab report is available in your account, and you can use the trends feature to monitor these markers over time if you retest in the future.

How can I naturally support immune system balance?
While autoimmune antibody levels aren't controlled by lifestyle alone, some habits can help support overall immune balance and reduce inflammation. Eating an anti-inflammatory diet rich in fruits, vegetables, and omega-3 fats, getting regular moderate exercise, managing stress through sleep and relaxation techniques, and avoiding smoking can all help your body function better. These steps won't eliminate autoantibodies but can help you feel your best while you monitor your condition.
When will I get my results?
Results for this panel are typically ready within about 7 days of your sample being tested at the lab. If your initial screen is positive, the reflex testing for the specific antibodies is done automatically on the same sample, so you don't need to submit a new one or wait for a separate order. You'll get a notification as soon as your full results are available in your account.
Who should consider this test?
This test is a good fit for adults with symptoms like skin tightening, joint stiffness, Raynaud's-like color changes in the fingers, or unexplained fatigue that could suggest an autoimmune process. It's also worth considering if a close family member has been diagnosed with systemic sclerosis or a related autoimmune condition. People who've had vague, hard-to-explain symptoms for months without answers often use this test as a starting point.
What symptoms indicate I may need this test?
Common symptoms that lead people to this test include skin thickening or tightening (especially on the hands and face), joint pain and stiffness, fingers that turn white or blue in the cold, difficulty swallowing, and persistent fatigue. Some people also notice small red spots on the skin or shortness of breath. If you're noticing a combination of these symptoms, especially skin changes, this panel can help clarify what's going on.
What does a positive ANA result mean?
A positive ANA result means your body is producing antibodies that target your own cell nuclei, which can happen with several autoimmune conditions, not just systemic sclerosis. It doesn't automatically mean you have a disease — some healthy people test positive too. That's why this panel automatically runs three more specific antibody tests when the screen is positive, to help figure out what the positive result might actually mean for you.
What causes a positive ANA or abnormal antibody result?
Positive ANA and related antibody results happen when your immune system mistakenly creates antibodies against your own tissues, which is the hallmark of autoimmune conditions like systemic sclerosis, lupus, and others. Triggers can include genetics, certain infections, prolonged stress, and in rare cases certain medications. Because many things can trigger a positive result, it's important to look at your symptoms and other test results together rather than the ANA alone.
How often should I retest?
If your results come back negative and you're not having symptoms, retesting usually isn't necessary unless new symptoms develop. If you test positive or have ongoing symptoms, retesting every 6 to 12 months can help you track whether antibody levels or patterns are changing over time. Using the trends feature in your account makes it easy to compare results side by side across multiple tests.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Antinuclear Antibody (ANA) Screen, IFA Negative
Demo results
Negative (Normal) Positive (Reflex Testing Triggered)
Negative

What this means

A negative result means no significant antinuclear antibodies were detected, making an autoimmune condition like systemic sclerosis less likely. This lowers the chance of the disease but doesn't rule it out completely, especially if symptoms persist. No reflex antibody testing is triggered when the screen is negative.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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ANA Screen with Reflex Testing for Autoimmune Symptoms

  • Screen for autoimmune warning signs
  • Check joint pain and skin changes
  • Detect early systemic sclerosis symptoms
$338
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.