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Autoimmune ANA and Sjogren's antibody panel for diagnosing joint pain and dryness

Sjogren's Syndrome Antibody Panel (ANA, SSA, SSB, RF)

ANA Screen,IFA, with Reflex to Titer and Pattern/Sjogren's Panel 2

  • Screen for Sjogren's syndrome markers
  • Detect autoimmune joint pain causes
  • Check dry eyes and mouth causes
$1167
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing dry eyes, dry mouth, joint pain, or fatigue that won't go away, and you're wondering if an autoimmune condition like Sjogren syndrome could be the cause. It's also useful if you've had unclear symptoms for a while and want a broad look at whether your immune system is attacking your own body. This panel screens for several related autoimmune markers at once instead of just one.

What's included in this test?

This panel checks for several different autoimmune antibody markers at the same time, which helps because autoimmune conditions like Sjogren syndrome often overlap with other immune issues. Testing multiple markers together gives a fuller picture than checking just one antibody, since a single negative result doesn't rule out an autoimmune process, and a positive ANA result gets automatically followed up with more detailed titer and pattern testing.

What happens after I get my results?

Your results will show up in your account with each marker explained alongside its normal range, so you can see exactly what was tested and how your numbers compare. If your ANA screen comes back positive, the lab automatically runs additional titer and pattern testing on the same sample, so you get a fuller picture without needing a second draw. Depending on what you see, next steps might include tracking symptoms over time, retesting in a few months, or seeking medical care sooner if you have severe or worsening symptoms. You can download a full lab report anytime and use the trends feature to watch how your levels change over future tests.

How can I naturally support immune system balance?
While you can't cure an autoimmune condition with lifestyle changes alone, some habits may help calm inflammation and support overall immune health. Getting consistent sleep, managing stress through activities like walking or meditation, and eating an anti-inflammatory diet rich in vegetables, omega-3s, and whole foods are good starting points. Staying hydrated and using artificial tears or saliva substitutes can also ease dryness symptoms if they're bothering you. If symptoms are significant or getting worse, don't rely on lifestyle changes alone — seek medical care.
When will I get my results?
Results are typically ready within about 7 days of your blood draw. This timeframe can vary slightly if the initial ANA screen comes back positive, since the lab needs to run the automatic reflex tests for titer and pattern before finalizing your report. You'll get a notification as soon as everything is ready to view in your account.
Who should consider this test?
This panel is a good fit for anyone with ongoing symptoms like dry eyes, dry mouth, unexplained joint pain, or fatigue that hasn't been explained by other causes. It's also worth considering if autoimmune disease runs in your family or if you've had inconclusive results from a basic antibody test before. People already managing one autoimmune condition who want to check for overlapping issues, like thyroid or liver-related autoimmunity, may also benefit.
What symptoms indicate I may need this test?
Common signs include persistent dry eyes or dry mouth, joint pain or swelling, unusual fatigue, skin rashes, or mouth sores that don't have a clear explanation. Some people also notice dental problems from reduced saliva or a general sense of feeling unwell without a clear cause. If these symptoms have lasted for weeks or months, this panel can help clarify whether an autoimmune process is involved.
What does a positive ANA result mean?
A positive ANA means your immune system is producing antibodies that target your own cell nuclei, which can happen in several autoimmune conditions, including Sjogren syndrome and lupus. It doesn't automatically mean you have a specific disease — some healthy people have a positive ANA with no illness at all. That's why this panel also checks the titer (how concentrated the antibodies are) and pattern, plus other specific antibodies like SSA and SSB, to help narrow down what's going on.
What causes a positive result on this panel?
Positive results usually reflect an autoimmune process where your immune system mistakenly targets your own tissues, such as glands that produce tears and saliva in Sjogren syndrome. Genetics, certain infections, and hormonal factors are all thought to play a role in why this happens. Some medications and other autoimmune conditions can also trigger a positive ANA or related antibody, which is why the pattern and titer results matter for interpretation.
How often should I retest?
If your results are negative but symptoms continue, retesting in 3-6 months can be helpful since autoimmune markers can become detectable over time. If you already have a diagnosed autoimmune condition, periodic retesting can help you and your care routine track whether markers like RF or TPO antibodies are changing. Using the trends feature in your account makes it easy to spot patterns across multiple tests over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Demo results
Antinuclear Antibody (ANA) Screen, IFA Negative
Demo results
Negative Positive
Negative

What this means

A negative ANA result means no significant antinuclear antibodies were detected in your sample, which makes autoimmune conditions like Sjogren syndrome or lupus less likely. Most people with a negative ANA also test negative on the more specific antibody markers in this panel. If you still have symptoms like dry eyes or joint pain, it may be worth monitoring and retesting later since some autoimmune markers develop over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Sjogren's Syndrome Antibody Panel (ANA, SSA, SSB, RF)

  • Screen for Sjogren's syndrome markers
  • Detect autoimmune joint pain causes
  • Check dry eyes and mouth causes
$1167
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.