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ANA screen test for adults with suspected autoimmune or connective tissue symptoms

ANA Screen Test for Autoimmune & Connective Tissue Symptoms

ANA Screen,IFA, with Reflex to Titer and Pattern/Mixed Connective Panel 2

  • Screen for autoimmune antibody activity
  • Check joint pain and fatigue causes
  • Detect early connective tissue symptoms
$49
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you're experiencing joint pain, unexplained fatigue, skin rashes, or muscle weakness that could point to an autoimmune condition. It screens for antinuclear antibodies (ANA), which the body sometimes makes when the immune system mistakenly attacks its own tissues. It's especially useful if you or your doctor suspect mixed connective tissue disease, lupus, or a related autoimmune disorder.

What's included in this test?

This panel starts with a broad ANA screen, which acts like a first checkpoint for autoimmune activity in the body. If that screen is positive, the lab automatically runs follow-up tests that look at antibody patterns and specific markers, which helps narrow down what type of autoimmune condition might be present rather than leaving you with just a vague 'yes or no' answer.

What happens after I get my results?

Your results will show up in your online account, with each value's normal range clearly explained so you know what's typical versus what stands out. If your ANA screen comes back positive, the report will also include the reflex results (titer, pattern, and specific antibodies) to help make sense of the finding, and retesting or symptom tracking over time is a reasonable next step. You can download a standard lab report anytime, and the trends feature lets you compare results if you test again in the future. If any result looks concerning or you have severe symptoms like unexplained swelling or extreme fatigue, consider seeking medical care promptly.

How can I naturally support immune system balance?
Getting consistent sleep, managing stress, and eating an anti-inflammatory diet rich in vegetables, omega-3s, and whole foods can help support overall immune balance. Regular moderate exercise and avoiding excessive alcohol or smoking also play a role in keeping inflammation in check. These habits won't cure an autoimmune condition, but they can help manage symptoms and support general wellbeing alongside any testing you do.
When will I get my results?
Results for this panel are typically available within about 7 days of your lab visit, since the reflex tests (if triggered by a positive screen) take a bit of extra lab processing time. You'll get a notification once results are ready to view in your account.
Who should consider this test?
This test is a good fit for anyone with persistent, unexplained symptoms like joint pain, fatigue, rashes, or muscle aches that haven't been explained by other causes. It's also useful for people with a family history of autoimmune disease who want a baseline check. If you've already been told you might have an autoimmune condition, this panel can help clarify which one.
What symptoms indicate I may need this test?
Common signs include ongoing joint pain or stiffness, unexplained skin rashes (especially ones that worsen in sunlight), persistent fatigue, muscle weakness, and unexplained fevers. Some people also notice hair thinning, dry eyes or mouth, or Raynaud's-like symptoms (fingers turning white or blue in the cold). If several of these show up together and don't have an obvious cause, this test can help investigate further.
What does a positive ANA result mean?
A positive ANA result means your immune system is producing antibodies that target your own cell nuclei, which can happen in autoimmune diseases like lupus, mixed connective tissue disease, or systemic sclerosis. It doesn't automatically mean you have a disease — some healthy people have mildly positive ANA results with no illness at all. That's why this panel automatically runs follow-up tests (titer, pattern, and specific antibodies) to help clarify what a positive result actually means for you.
What causes a positive ANA result?
A positive ANA can be triggered by autoimmune diseases such as lupus, mixed connective tissue disease, or systemic sclerosis, but it can also show up due to certain infections, some medications, or even normal aging in a small percentage of healthy people. The titer (how diluted the sample can be and still show antibodies) and staining pattern seen under the microscope help distinguish a meaningful result from a low-level, less significant one. Family history of autoimmune conditions can also increase the chances of a positive result.
How often should I retest?
If your first ANA screen comes back negative and you have no new symptoms, there's usually no need to retest right away. If you had a positive result or your symptoms are changing or getting worse, retesting every few months (or as your symptoms evolve) can help track whether antibody levels or patterns are shifting. Keeping a symptom journal alongside retesting can make it easier to spot meaningful changes over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Antinuclear Antibodies (ANA), IFA Screen Negative
Demo results
Negative Positive
Negative

What this means

A negative ANA result means no significant antinuclear antibodies were detected, which makes autoimmune conditions like lupus or mixed connective tissue disease less likely. Most people with negative ANA results do not have an autoimmune disease causing their symptoms. If symptoms persist, other causes may need to be explored.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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ANA Screen Test for Autoimmune & Connective Tissue Symptoms

  • Screen for autoimmune antibody activity
  • Check joint pain and fatigue causes
  • Detect early connective tissue symptoms
$49
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.