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Amitriptyline drug level test for monitoring tricyclic antidepressant therapy safely

Amitriptyline Drug Level Blood Test

Amitriptyline

  • Check your antidepressant medication levels
  • Monitor treatment dose effectiveness safely
  • Screen for potential medication side effects
$247
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're currently taking amitriptyline (or its active form, nortriptyline) for depression and need to check how much of the medication is in your blood. It helps confirm you're getting enough of the drug to work, while also making sure the level isn't high enough to cause side effects. This is especially useful if you've had a dose change, started other medications, or are experiencing symptoms that could mean the dose needs adjusting.

What's included in this test?

This test measures the amount of amitriptyline and its active metabolite, nortriptyline, circulating in your blood. Checking both forms together matters because your body converts amitriptyline into nortriptyline, and looking at the combined level gives a clearer picture of your total drug exposure than checking amitriptyline alone.

What happens after I get my results?

Your results will show up in your account with the normal therapeutic range clearly explained next to your value. If your level falls outside the expected range, simple next steps include reviewing your dosing schedule and timing of your last dose before the blood draw, since this can affect the reading. The full lab report is available to download from your account at any time, and you can use the trends feature to track your levels over multiple tests if you're retesting periodically.

How can I naturally support healthy mood and reduce reliance on medication side effects?
While you shouldn't change your medication routine without guidance, some everyday habits can support how you feel alongside treatment. Regular physical activity, consistent sleep schedules, reducing alcohol intake, and eating balanced meals can all help support mood and may reduce some side effects like drowsiness or grogginess. Staying well-hydrated and avoiding caffeine late in the day can also help with sleep quality while on this type of medication.
When will I get my results?
Results are typically ready within about 7 days of your blood draw. Once processed, they'll be posted directly to your account, and you'll be able to view your amitriptyline and nortriptyline levels along with the reference range used to interpret them.
Who should consider this test?
Anyone currently prescribed amitriptyline who wants to confirm their dose is in a safe and effective range should consider this test. It's also useful if you've recently changed your dose, added a new medication that might interact with amitriptyline, or noticed new symptoms like unusual drowsiness, dizziness, or a fast heartbeat. Periodic monitoring is also common practice for people on long-term tricyclic antidepressant therapy.
What symptoms indicate I may need this test?
Symptoms like unusual drowsiness, confusion, blurred vision, a fast or irregular heartbeat, or dizziness could mean your amitriptyline level is too high. On the other hand, if your depression symptoms haven't improved or seem to be getting worse despite taking your medication as prescribed, your level might be too low. Either situation is a good reason to check your blood level.
What does high amitriptyline mean?
A high level means more of the drug is in your system than the typical effective range, which raises the risk of side effects like severe drowsiness, confusion, tremors, or heart rhythm changes. This can happen if the dose is too high, if you've missed doses and then taken extra, or if another medication is slowing down how your body clears amitriptyline. If your level is significantly elevated and you're experiencing symptoms like a racing heart or severe confusion, seek medical care right away.
What does low amitriptyline mean?
A low level suggests the medication may not be reaching a strong enough concentration to effectively manage depression symptoms. This can happen if a dose is missed, taken inconsistently, or if your body processes the drug faster than average. It's worth reviewing how consistently the medication is being taken and the exact timing of your last dose relative to the blood draw before assuming the dose itself needs to change.
How often should I retest?
Retesting frequency depends on how stable your symptoms and dose have been, but it's common to check levels after any dose adjustment, after starting or stopping other medications, or every few months during long-term therapy. If you're feeling well and your dose hasn't changed, less frequent testing may be reasonable. Tracking your results over time using the trends feature can help you and anyone helping manage your treatment spot patterns.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Amitriptyline (plus Nortriptyline) 185 ng/mL
Demo results
Below 120 ng/mL (Subtherapeutic) 120-250 ng/mL (Therapeutic) Above 250 ng/mL (Potentially Toxic)
185 ng/mL

What this means

A combined amitriptyline and nortriptyline level of 185 ng/mL falls within the typical therapeutic range used to monitor treatment. This suggests the medication is present at a level generally associated with therapeutic effect without being in the higher-risk zone. Individual response can still vary, so this value should be considered alongside how you're feeling overall.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Amitriptyline Drug Level Blood Test

  • Check your antidepressant medication levels
  • Monitor treatment dose effectiveness safely
  • Screen for potential medication side effects
$247
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.