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AFP-L3 liver cancer risk test for people with chronic liver disease or cirrhosis

AFP and AFP-L3 Liver Cancer Risk Blood Test

Alpha-Fetoprotein (AFP) and AFP-L3

  • Screen for liver cancer risk
  • Monitor chronic liver disease progress
  • Track abnormal liver protein changes
$341
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're living with chronic liver disease, hepatitis B or C, or cirrhosis and want to understand your risk of developing liver cancer. It's also useful if you've had unusual liver imaging results or a family history of liver cancer and want an early warning sign. Catching changes early gives you more options for follow-up care and monitoring.

What's included in this test?

This test measures two related markers: total AFP, a protein made by the liver, and AFP-L3, a specific form of that protein that rises more often when liver cancer risk is elevated. Looking at both together gives a clearer picture of liver health than either marker alone, especially for people already managing chronic liver disease.

What happens after I get my results?

Your results will show up in your account with each value's normal range clearly explained. If your levels are outside the expected range, next steps usually include retesting on a regular schedule or getting liver imaging to look more closely at what's happening. A downloadable lab report is available in your account anytime, and you can track your AFP and AFP-L3 levels over time using the trends feature to spot patterns early.

How can I naturally support liver health?
Cutting back on alcohol, avoiding unnecessary medications that stress the liver, and eating a diet rich in vegetables, lean protein, and whole grains can all help support liver function. Staying at a healthy weight and managing blood sugar also reduce strain on the liver. These habits won't replace monitoring, but they can support the organ while you track your results over time.
When will I get my results?
Results are typically ready within about 7 days of your blood draw. You'll get a notification as soon as they're posted to your account, where you can view the values alongside their reference ranges.
Who should consider this test?
People with chronic hepatitis B or C, cirrhosis, or a known history of liver disease are the main candidates for this test. It's also worth considering if you have a family history of liver cancer or if a previous scan showed something unusual in your liver. Regular monitoring is especially important if you fall into a higher-risk group.
What symptoms indicate I may need this test?
Unexplained weight loss, ongoing fatigue, abdominal pain or swelling, and yellowing of the skin or eyes (jaundice) can all be signs worth checking out, especially if you already have liver disease. A loss of appetite or a feeling of fullness after eating small amounts can also be a signal. These symptoms alone don't confirm anything, but combined with known liver disease, they're a good reason to test.
What does high AFP mean?
A higher-than-normal AFP or AFP-L3 level can point to increased risk of liver cancer, especially in someone with existing liver disease, though it can also rise with liver inflammation or regeneration after injury. It doesn't mean cancer is present, but it's a signal that closer monitoring or imaging is a reasonable next step. Retesting helps confirm whether the level is trending up, staying steady, or coming back down.
What causes high AFP levels?
Chronic hepatitis, cirrhosis, active liver inflammation, and liver tumors are the most common causes of elevated AFP or AFP-L3. Sometimes liver regeneration after an injury or illness can also cause a temporary rise. Because there are several possible causes, one high result is best followed up with retesting or imaging rather than treated as a final answer.
How often should I retest?
If you have chronic liver disease, many people retest every 6 months as part of ongoing monitoring, but your pattern of results may call for more frequent checks. Tracking your levels over time in the trends feature makes it easier to notice whether a change is a one-time blip or a real trend. If a result is significantly elevated, retesting sooner rather than waiting the full interval is a good idea.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Alpha-Fetoprotein (AFP) 8.2 ng/mL
Demo results
Normal (0-8.5 ng/mL) Elevated (>8.5 ng/mL)
8.2 ng/mL

What this means

This result falls within the normal range, suggesting no current signal of increased liver cancer risk from this marker. People with chronic liver disease should still continue regular monitoring since levels can change over time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

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AFP and AFP-L3 Liver Cancer Risk Blood Test

  • Screen for liver cancer risk
  • Monitor chronic liver disease progress
  • Track abnormal liver protein changes
$341
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.