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Alpha-2-Macroglobulin test for liver, kidney, and joint health monitoring

Alpha-2-Macroglobulin Blood Test for Liver & Kidney Health

Alpha-2-Macroglobulin

  • Check liver and kidney function
  • Monitor chronic disease progression
  • Assess joint inflammation markers
$398
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First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing symptoms of liver problems, joint pain, or swelling that could point to kidney issues. It's also useful if you've been told you have a chronic liver condition, nephrotic syndrome, diabetes, or an autoimmune condition like rheumatoid arthritis and want to keep an eye on how your body is handling it. Many people also use it as a general marker of protein health in the body.

What happens after I get my results?

Your results will show up in your account with the normal range clearly explained next to your value, so you can see right away where you stand. Depending on whether your level is high or low, you might consider lifestyle changes like reducing alcohol intake, watching your blood sugar, or getting checked again in a few months to track any changes. You can download a standard lab report straight from your account at any time, and if you retest later, our trends feature lets you compare results side by side to see how things are moving.

What is Alpha-2-Macroglobulin and why does it matter?

Alpha-2-Macroglobulin is a protein made by your liver that helps fight inflammation and clean up other proteins in your blood. Doctors and labs use it as a clue about how well your liver, kidneys, and joints are functioning. Because it shifts with certain chronic conditions, tracking it over time can help you notice patterns before bigger problems show up.

When will I get my results?
Most results are ready within about 7 days after your blood is drawn at the lab. You'll get a notification as soon as your report is available in your account, so there's no need to call or wait on hold. If anything looks urgent, the report will flag it clearly.
Who should consider this test?
This test is a good fit for people managing chronic liver disease, diabetes, or kidney-related conditions like nephrotic syndrome who want an extra data point on their health. It's also worth considering if you have rheumatoid arthritis or unexplained joint pain and want to understand what might be going on. Anyone curious about their liver and protein health in general can also use it as a baseline check.
What symptoms indicate I may need this test?
Swelling in the legs or belly, unusual fatigue, joint pain and stiffness, or changes in urine (like foaming or reduced amounts) can all be reasons to check this marker. If you've noticed unexplained weight changes alongside these symptoms, that's another signal worth looking into. These symptoms alone don't confirm anything, but they're a good reason to get a clearer picture with a blood test.
How can I naturally support healthy liver and kidney function?
Cutting back on alcohol and processed foods gives your liver less work to do and can help keep this marker in a healthy range. Staying hydrated and eating a diet rich in vegetables, lean protein, and fiber supports both liver and kidney health. Regular movement and maintaining a healthy weight also reduce strain on these organs over time.
What does a high Alpha-2-Macroglobulin result mean?
A higher than normal result can be linked to chronic liver conditions, nephrotic syndrome, or diabetes, since the body sometimes produces more of this protein in response to those conditions. It doesn't automatically mean something is seriously wrong, but it's worth paying attention to alongside your other symptoms. Cutting back on alcohol, managing blood sugar, and retesting in a few months are practical next steps.
What does a low Alpha-2-Macroglobulin result mean?
A lower than normal result has been associated with conditions like pancreatitis, rheumatoid arthritis, and multiple myeloma. If your level comes back low, it can help to look at your overall symptom picture, like joint pain or digestive issues, and consider retesting to confirm the pattern. If you're feeling seriously unwell, especially with severe abdominal pain, seek medical care right away.
How often should I retest?
If you're managing a chronic condition like liver disease or diabetes, retesting every 3-6 months can help you track trends over time. If your first result was in the normal range and you're just checking as a baseline, retesting once a year is usually enough. Your trends feature will show you these changes clearly so you know when a retest is worth doing sooner.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Alpha-2-Macroglobulin 210 mg/dL
Demo results
Low (<110 mg/dL) Normal (110-200 mg/dL) High (>200 mg/dL)
210 mg/dL

What this means

Your Alpha-2-Macroglobulin level is slightly above the typical range, which can sometimes be seen with chronic liver conditions, diabetes, or kidney-related issues like nephrotic syndrome. This single result isn't a diagnosis on its own, but it's worth watching alongside how you're feeling overall.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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Alpha-2-Macroglobulin Blood Test for Liver & Kidney Health

  • Check liver and kidney function
  • Monitor chronic disease progression
  • Assess joint inflammation markers
$398
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.