What's this test for?

This test is ideal if you're experiencing unexplained shortness of breath, wheezing, or early-onset emphysema, especially if you've never smoked. It's also helpful if liver problems run in your family or if lung disease seems to appear younger than expected across generations. Checking for Alpha-1-Antitrypsin deficiency can explain symptoms that don't add up with typical asthma or COPD causes.

What's included in this test?

This test measures the amount of Alpha-1-Antitrypsin protein in your blood and checks for common gene mutations that cause this protein to be low or abnormal. Together, these two pieces of information show whether your body makes enough of this protective protein and whether a genetic variant is the reason behind low levels, which matters because low AAT lets damaging enzymes harm your lungs and liver over time.

What happens after I get my results?

Your results will show up in your account along with a plain-language explanation of what the normal range means for this protein and its gene variants. If your levels come back low or a mutation is found, next steps usually include avoiding smoke and lung irritants, discussing family screening, and rechecking levels periodically to track any changes. You can download a standard lab report anytime from your account, and the trends feature lets you compare results if you test again in the future. If your results show very low protein levels along with breathing trouble, seek medical care promptly.

How can I naturally support lung and liver health?

Avoiding cigarette smoke and secondhand smoke is the single biggest step you can take, since smoking dramatically speeds up lung damage in people with this condition. Staying away from dust, chemical fumes, and heavy air pollution also helps protect your lungs. Eating a balanced diet, limiting alcohol, staying up to date on vaccines like flu and pneumonia shots, and staying physically active all support your lungs and liver as well.

When will I get my results?

Results are typically ready within about 7 days of your blood draw. Because this test involves both a protein level and genetic analysis, it takes a bit longer than a routine blood test. You'll get a notification as soon as your results are posted to your account.

Who should consider this test?

This test is a good idea if you have early or unexplained lung disease, especially before age 45, or if you've been diagnosed with COPD or emphysema without a strong smoking history. It's also worth considering if you have unexplained liver disease, cirrhosis of unknown cause, or a family member diagnosed with Alpha-1-Antitrypsin deficiency. Siblings and children of someone with this condition often consider testing too, since it's inherited.

What symptoms indicate I may need this test?

Watch for ongoing shortness of breath, wheezing, or a chronic cough that doesn't have a clear cause, particularly if you're younger than typical COPD patients. Repeated lung infections, reduced exercise tolerance, and unexplained fatigue can also be signs. On the liver side, yellowing skin or eyes, unexplained swelling in the belly or legs, or abnormal liver blood work can point to this condition as well.

What does a low Alpha-1-Antitrypsin level mean?

A low level means your body isn't producing enough of this protective protein, which normally shields your lungs from damage caused by inflammation. Over time, low levels can allow lung tissue to break down faster, raising the risk of emphysema, and can also cause certain mutated protein forms to build up and damage the liver. Combined with a mutation finding, a low level helps confirm whether Alpha-1-Antitrypsin deficiency is the cause of your symptoms.

What causes low Alpha-1-Antitrypsin levels?

The most common cause is an inherited gene mutation passed down from one or both parents, which reduces how much of this protein your liver makes or releases properly. Some mutations cause the protein to get stuck in the liver instead of reaching the bloodstream, which is why both low blood levels and liver damage can happen together. Because it's genetic, levels don't change due to diet or lifestyle, though lifestyle choices affect how much damage low levels eventually cause.

How often should I retest?

Since Alpha-1-Antitrypsin deficiency is genetic, the mutation result itself won't change and doesn't need repeating. However, if you're diagnosed with a deficiency, periodic monitoring of lung function and liver health is reasonable, often yearly or as advised based on your specific mutation and symptoms. Retesting the protein level itself is less common but may be repeated if there's a reason to recheck your baseline.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Alpha-1-Antitrypsin Test - Lung & Liver Disease Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Alpha-1-Antitrypsin Deficiency Test — Lung & Liver Health

Alpha-1-Antitrypsin (AAT) Quantitation and Mutation Analysis

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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Alpha-1-Antitrypsin Deficiency Test — Lung & Liver Health

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

1,000,000+ blood tests later, here's what our customers say