What's this test for?

This test is ideal if you're experiencing unexplained breathing problems, early-onset emphysema, or chronic bronchitis that doesn't fit the usual pattern (like being a non-smoker or younger than typical). It's also helpful if you or a family member has had unexplained liver disease, jaundice, or cirrhosis, especially in infancy. Many people take this test because a close relative has been diagnosed with Alpha-1 Antitrypsin deficiency and they want to know their own genetic status.

What's included in this test?

This test identifies your specific Alpha-1 Antitrypsin (AAT) phenotype rather than a list of separate biomarkers. Knowing your phenotype matters because certain inherited variants, like ZZ, SS, or SZ, are strongly linked to a higher risk of lung disease in adults and liver disease starting in infancy. Identifying your exact phenotype helps clarify your personal risk level and whether extra monitoring makes sense.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what your specific phenotype means and how it compares to the normal range. If your phenotype shows an increased risk for lung or liver problems, practical next steps include avoiding smoking and airborne irritants, limiting alcohol to protect your liver, and getting periodic lung function checks. You can download a standard lab report directly from your account at any time, and if you retest in the future, our trends feature lets you track any related follow-up markers over time.

How can I naturally support healthy lungs and liver?

Avoiding cigarette smoke and secondhand smoke is the single biggest step you can take to protect your lungs if you carry an AAT risk variant. Limiting alcohol intake and maintaining a healthy weight both help reduce strain on your liver. Regular moderate exercise supports lung capacity over time, and staying up to date on vaccines like the flu shot and pneumonia vaccine can help prevent infections that stress the lungs.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as your report is available in your online account. Turnaround can occasionally vary slightly depending on lab volume, but you can always check your account for the most current status.

Who should consider this test?

This test is a good fit for adults with unexplained emphysema or chronic bronchitis, especially if they've never smoked or are younger than the typical age for these conditions. It's also worth considering if you have a family history of Alpha-1 Antitrypsin deficiency, unexplained liver disease, or infant relatives who had unexplained cirrhosis or hepatitis. People planning a family who want to understand inherited risk may also find this test useful.

What symptoms indicate I may need this test?

Watch for shortness of breath, wheezing, or a chronic cough that doesn't go away, particularly if you're a nonsmoker or under 45. Recurrent lung infections, unexplained fatigue, or reduced exercise tolerance can also be signs worth investigating. On the liver side, unexplained jaundice (yellowing skin or eyes), abdominal swelling, or abnormal liver tests in a baby or adult can point to an AAT-related issue.

What is Alpha-1 Antitrypsin deficiency and why does it matter?

Alpha-1 Antitrypsin is a protein made by your liver that protects your lungs from damage caused by everyday inflammation. When you inherit certain gene variants, your body makes less of this protective protein or a faulty version of it, which can let lung tissue break down over time and cause the protein to build up in the liver. This matters because it's a leading genetic cause of emphysema and can also cause liver disease, sometimes starting in early childhood.

What causes an abnormal AAT phenotype result?

An abnormal phenotype result comes from inheriting one or two copies of a variant AAT gene from your parents, most commonly labeled S or Z instead of the typical M variant. This is purely genetic, meaning it's not caused by lifestyle or environment, though smoking and pollution exposure can make lung damage progress faster if you carry a risk variant. Having one variant copy generally carries lower risk than having two, which is why knowing your exact phenotype combination matters.

What should I do if my results show a risk variant?

If your phenotype shows an increased risk, avoiding smoking and reducing exposure to dust, fumes, and air pollution becomes especially important for protecting your lungs. Consider periodic lung function testing and liver check-ins to catch any changes early. Sharing your results with close biological relatives can also help them decide if they want to get tested, since this condition runs in families.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

AAT Phenotype Test - Lung & Liver Risk Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Alpha-1 Antitrypsin (AAT) Phenotype Test

Alpha-1-Antitrypsin (AAT) Phenotype

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Alpha-1 Antitrypsin (AAT) Phenotype Test

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

1,000,000+ blood tests later, here's what our customers say