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ADAMTS13 activity test for diagnosing rare blood clotting disorder TTP

ADAMTS13 Activity Blood Test with Inhibitor Reflex

ADAMTS13 Activity with Reflex to Inhibitor

  • Detect rare blood clotting enzyme deficiency
  • Screen for unusual bruising or fatigue causes
  • Monitor risk for dangerous blood clots
$556
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained bruising, small red or purple spots on your skin, unusual tiredness, confusion, or signs of low platelet counts. It's also useful if you have a family history of a rare blood clotting disorder called TTP (thrombotic thrombocytopenic purpura), or if you've had unexplained blood clots along with low platelets and red blood cell breakdown. Your results help identify whether an enzyme problem in your blood is contributing to these symptoms.

What's included in this test?

This test measures the activity of a single, specialized enzyme in your blood that plays a key role in normal blood clotting. Because this enzyme controls how certain clotting proteins are broken down, checking its activity level helps determine whether a shortage of it—or an antibody blocking it—could be causing clotting or bleeding problems. If your initial result comes back low, a reflex test automatically checks for inhibitor antibodies to pinpoint the underlying cause.

What happens after I get my results?

Your results will be available in your account, with each value's normal range explained so you understand exactly what it means. If your ADAMTS-13 activity is low, next steps typically include follow-up testing to check for an inhibitor and prompt attention since very low levels can be serious. The standard lab report is downloadable directly from your account, and you can track this result over time using the trends feature if you retest in the future. If your result is severely low along with symptoms like confusion, unusual bruising, or extreme fatigue, seek medical care right away.

How can I naturally support healthy blood clotting function?
While you can't naturally boost ADAMTS-13 activity itself, you can support overall blood and vascular health with a balanced diet rich in leafy greens, adequate hydration, and regular gentle exercise. Avoiding excessive alcohol and managing stress can also help support healthy blood cell function. However, if your levels are abnormally low, these lifestyle steps are not a substitute for prompt medical attention, since this condition can become serious quickly.
When will I get my results?
Results for this test are typically ready within about 7 days of your sample being collected at the lab. Because this is a specialized test with a reflex component for inhibitor testing (if needed), turnaround can occasionally take a little longer. You'll receive a notification as soon as your results are posted to your account.
Who should consider this test?
This test is worth considering if you have unexplained low platelet counts, unusual bruising or bleeding, or episodes of confusion combined with kidney problems. People with a family history of TTP, or those who've previously been diagnosed with an autoimmune-related clotting disorder, may also want this test. It's commonly used to investigate or monitor this rare but serious condition.
What symptoms indicate I may need this test?
Watch for symptoms like easy bruising, tiny red or purple dots on your skin (called petechiae), extreme fatigue, confusion or headaches, fever, and dark urine. These can signal that your platelets are low and your red blood cells are being damaged, both of which are hallmark signs of TTP. If these symptoms are sudden or severe, seek medical care immediately rather than waiting for standard test results.
What is ADAMTS-13 and why does it matter?
ADAMTS-13 is an enzyme in your blood that trims down large, sticky clotting proteins so your blood doesn't clot excessively. When this enzyme doesn't work properly—either because you're born with too little of it or your body makes antibodies against it—your blood can form dangerous small clots throughout your body. This is why checking its activity level matters for diagnosing and monitoring the rare disorder TTP.
What does a low ADAMTS-13 result mean?
A low result means your body doesn't have enough active enzyme to properly break down certain clotting proteins, which raises your risk of dangerous small blood clots and low platelet counts. This can be caused by an inherited gene mutation or, more commonly, by antibodies your immune system has made against the enzyme. Very low levels combined with symptoms like confusion or unusual bruising need urgent medical attention.
What causes low ADAMTS-13 activity?
Low activity is usually caused by one of two things: an inherited genetic mutation that's present from birth, or an acquired autoimmune condition where your body produces antibodies that block the enzyme's function. The acquired form is more common in adults and can sometimes be triggered by pregnancy, infections, certain medications, or underlying autoimmune conditions. The reflex inhibitor test included with this panel helps determine which type you may have.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
ADAMTS-13 Activity 0.65 IU/mL
Demo results
Low (<0.4 IU/mL) Normal (0.4-1.3 IU/mL) High (>1.3 IU/mL)
0.65 IU/mL

What this means

This result falls within the normal range, meaning your enzyme is working well to keep your blood clotting properly balanced. A result like this suggests your risk for TTP-related clotting problems from this enzyme is low. Levels below 0.4 IU/mL would raise concern for TTP, especially with related symptoms.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
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ADAMTS13 Activity Blood Test with Inhibitor Reflex

  • Detect rare blood clotting enzyme deficiency
  • Screen for unusual bruising or fatigue causes
  • Monitor risk for dangerous blood clots
$556
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.