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AML prognostic panel testing FLT3, NPM1, CEBPA gene mutations for leukemia risk

AML Prognostic Gene Panel (FLT3, NPM1, CEBPA)

Acute Myeloid Leukemia Prognostic Panel (Normal Karyotype)

  • Assess leukemia treatment response likelihood
  • Screen for key gene mutations
  • Clarify disease risk and outlook
$5458
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
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Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay
  • Many results come back overnight *
  • 90-day money back guarantee
  • Save time & skip the doctor’s office
  • Lab visit as quick as 10 minutes
  • Results explained, with clear next steps
  • LegitScript certified
  • No questions asked refunds
  • The price you see is the price you pay

What's this test for?

This test is ideal if you or someone you care for has been diagnosed with acute myeloid leukemia (AML) that shows a normal karyotype on cytogenetic testing. It looks at specific gene changes that help clarify how the disease is likely to behave and respond to treatment. This information is often used alongside other clinical findings to understand risk level and guide treatment decisions.

What's included in this test?

This panel looks at three gene changes that are known to affect how AML behaves and responds to treatment. Each one gives different information: one is linked to better long-term outcomes, one signals a strong response to initial chemotherapy, and one is associated with a more aggressive disease course. Looking at all three together gives a fuller picture of prognosis than any one marker alone.

What happens after I get my results?

Your results will be available in your account, with each gene finding explained in plain language along with what a positive or negative result typically means. Because this is a specialized prognostic test tied to an active AML diagnosis, next steps usually involve discussing findings with your treatment team as soon as possible rather than waiting for a routine retest. A downloadable standard lab report is available in your account for your records, and you can track any repeat testing over time using the trends feature.

How can I naturally support my treatment recovery?
While gene mutations like these can't be changed through lifestyle choices, supporting your body during AML treatment can still help you feel better day to day. Eating enough protein and calories, staying hydrated, and resting when needed can help your body handle chemotherapy. Gentle movement, when your care team says it's safe, and avoiding infections by practicing good hygiene are also helpful. These steps support your overall wellbeing but don't replace your prescribed treatment plan.
When will I get my results?
Results for this panel are typically ready within about 7 days after your sample is collected. Because this test involves detailed genetic analysis, it takes a bit longer than routine bloodwork. You'll be notified as soon as your results are posted to your account.
Who should consider this test?
This test is meant for people who have already been diagnosed with acute myeloid leukemia and whose cancer cells show a normal karyotype (no visible chromosome abnormalities under standard testing). It's typically ordered as part of a broader diagnostic workup rather than as a general screening test. If you're unsure whether this applies to your situation, check with your treatment team before ordering.
What symptoms indicate I may need this test?
This isn't a symptom-based screening test — it's used after an AML diagnosis has already been made, often through a bone marrow biopsy or blood count abnormalities. Symptoms that typically lead to an AML diagnosis include unusual fatigue, easy bruising or bleeding, frequent infections, and unexplained weight loss. If you're experiencing these symptoms and haven't been diagnosed yet, this specific panel isn't the right starting point.
What does a positive FLT3 result mean?
A positive FLT3 internal tandem duplication result means this particular gene change is present in the leukemia cells, which is generally associated with a shorter disease-free period and a higher chance of relapse. This doesn't mean treatment won't work, but it may influence how aggressively the condition is monitored and treated. Discuss this finding with your treatment team so it can be factored into your overall care plan.
What does a positive NPM1 result mean?
A positive NPM1 mutation, especially without a FLT3 mutation present, is generally considered good news. It's linked to a better response to initial chemotherapy and a more favorable long-term outlook. This result is often used to help decide how intensive treatment needs to be.
How often should I retest?
This panel is typically run once at diagnosis to establish baseline prognostic information, since these gene mutations are used to characterize the original leukemia rather than being routinely rechecked. Your treatment team may recommend related testing (such as minimal residual disease monitoring) at different points during treatment. Repeat testing of this specific panel is uncommon unless there's a clinical reason, such as relapse or a new diagnosis.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
NPM1 Mutation Positive
Demo results
Negative (Not Detected) Positive (Detected)
Positive

What this means

A positive NPM1 result means this gene mutation was found in the leukemia cells. When present without a FLT3 mutation, this is generally linked to a more favorable prognosis and better response to initial chemotherapy.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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AML Prognostic Gene Panel (FLT3, NPM1, CEBPA)

  • Assess leukemia treatment response likelihood
  • Screen for key gene mutations
  • Clarify disease risk and outlook
$5458
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.