What's this test for?

This test is ideal if you're experiencing unexplained blood clots, or if you've had a personal or family history of deep vein thrombosis (DVT) or pulmonary embolism. It's also useful if you're planning pregnancy or hormone therapy and want to understand your clotting risk beforehand. Many people take this test after a blood clot event to find out if a genetic cause is involved.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what normal versus abnormal ranges mean for this test. If your results show APC resistance or the Factor V Leiden mutation, practical next steps include discussing clot-prevention strategies during high-risk situations like surgery, pregnancy, or long flights, and staying alert for symptoms like leg swelling or pain. You can download a standard lab report anytime from your account, and since this is a one-time genetic-type result, ongoing retesting typically isn't needed, though you can track it alongside other health markers using the trends feature.

What's included in this test?

This test includes the Activated Protein C (APC) resistance functional assay, with a reflex to Factor V Leiden mutation genetic testing if the initial result is abnormal. The APC resistance assay measures how your blood clots in response to activated protein C, a natural clot-regulating protein. If resistance is detected, the Factor V Leiden genetic test confirms whether an inherited mutation is the cause, since over 95% of APC resistance cases stem from this mutation. Together these tests pinpoint whether you have a genetic tendency toward abnormal blood clotting.

How can I naturally support healthy blood flow?

Staying well hydrated, moving regularly (especially during long trips or after surgery), and avoiding prolonged sitting all help support healthy circulation. Maintaining a healthy weight and not smoking also lower overall clotting risk. These habits won't change your genetics, but they reduce the chances that a clotting tendency turns into an actual clot.

When will I get my results?

Results are typically ready within about 7 days of your sample being processed. You'll receive a notification once they're available in your secure online account, where you can view and download the full report.

Who should consider this test?

People who've had an unexplained blood clot, especially at a young age, are good candidates for this test. It's also worth considering if a close family member has been diagnosed with Factor V Leiden or has a history of clotting problems. Those planning pregnancy, birth control, or hormone replacement therapy with a family history of clots may also want this information beforehand.

What symptoms indicate I may need this test?

Watch for symptoms like unexplained leg swelling, pain, warmth, or redness, which can signal a deep vein clot. Sudden shortness of breath or chest pain can indicate a clot has traveled to the lungs and needs urgent attention. Recurrent miscarriages have also been linked to clotting disorders like Factor V Leiden.

What does a positive result for Factor V Leiden mean?

A positive result means you carry a genetic variant that makes your blood more prone to clotting than average. Having one copy raises your risk somewhat, while having two copies raises it more significantly. This doesn't mean you'll definitely develop a clot, but it does mean you should be extra cautious during high-risk situations like surgery, pregnancy, or long periods of immobility.

What causes APC resistance besides the Factor V Leiden mutation?

While the Factor V Leiden mutation accounts for the vast majority of APC resistance cases, other factors like pregnancy, certain autoimmune conditions, and estrogen-based medications can also cause temporary APC resistance without the genetic mutation being present. That's why this test specifically checks for the underlying genetic cause. Identifying the exact cause helps clarify whether the risk is lifelong or temporary.

What should I do if my results are abnormal?

If your test shows APC resistance or the Factor V Leiden mutation, share this information whenever you're preparing for surgery, starting hormonal medications, or planning a pregnancy, since these situations carry higher clotting risk. Staying active, avoiding long periods of sitting, and knowing the warning signs of a clot are practical everyday steps. If you notice sudden leg swelling, pain, chest pain, or shortness of breath, seek medical care right away, as these can be signs of a serious clot.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Factor V Leiden Test - Blood Clot Risk Screening

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Factor V Leiden Blood Clot Risk Test

Activated Protein C Resistance with Reflex to Factor V (Leiden) Mutation

Prescription & fees included

Easy to understand results

Fast & convenient

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Factor V Leiden Blood Clot Risk Test

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say