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ACTH stimulation test for adrenal function and Addison's disease evaluation

ACTH Stimulation Test for Adrenal Function & Addison's Disease

ACTH Stimulation, 2 Specimens

  • Check adrenal gland stress response
  • Screen for Addison's disease signs
  • Assess unexplained fatigue and weakness
$455
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, muscle weakness, unusual weight loss, low blood pressure, or dark patches on your skin. These can be signs that your adrenal glands aren't producing enough cortisol, a condition known as Addison's disease. The ACTH stimulation test checks how well your adrenal glands respond and helps confirm whether they're working properly.

What's included in this test?

This test measures cortisol levels at two different points in time, before and after a stimulating injection, to see how responsive your adrenal glands are. This two-specimen approach matters because a single cortisol reading can't tell the full story about adrenal function on its own. Comparing the two results gives a clearer picture of whether your adrenal glands are able to ramp up hormone production when needed.

What happens after I get my results?

Your results will show up in your account with each value's normal range clearly explained, so you can see exactly how your adrenal glands responded before and after stimulation. If your cortisol response is low, the report will outline next steps, such as retesting or seeking care promptly since adrenal insufficiency can be serious if untreated. You can download a standard lab report from your account at any time, and you'll be able to track your results over time using the trends feature if you retest in the future.

How can I naturally support adrenal health?
While you can't force damaged adrenal glands to work harder, you can support your body with consistent sleep, reducing chronic stress, and eating regular balanced meals to avoid blood sugar crashes. Limiting caffeine and alcohol can also ease the extra burden on your adrenal system. These habits won't replace treatment if your glands aren't functioning properly, but they can help you feel more stable day to day.
When will I get my results?
Results are typically ready within about 7 days of your blood draw. Once processed, they'll be uploaded directly to your secure online account, where you can view and download them at your convenience.
Who should consider this test?
This test is a good fit for anyone with ongoing fatigue, muscle weakness, unexplained weight loss, low blood pressure, or salt cravings that haven't gone away with lifestyle changes. It's also useful if you've noticed darkening of your skin, especially in creases or scars, which can be a classic sign of adrenal problems. People already diagnosed with an adrenal condition may also use this test to monitor how their glands are functioning.
What symptoms indicate I may need this test?
Common symptoms include persistent tiredness that doesn't improve with rest, muscle weakness, dizziness when standing up, low blood pressure, and unexplained weight loss. Some people also notice increased salt cravings, nausea, or darkened patches of skin. If you're dealing with several of these symptoms together, it's worth checking your adrenal function.
What is adrenal insufficiency and why does it matter?
Adrenal insufficiency happens when your adrenal glands don't make enough cortisol, a hormone that helps your body handle stress, regulate blood pressure, and manage energy levels. Left unaddressed, low cortisol can lead to serious fatigue, low blood pressure, and in severe cases, a dangerous adrenal crisis. Catching it early with a simple test can help you get ahead of bigger health problems.
What does a low cortisol response mean?
If your cortisol doesn't rise much after the stimulation injection, it suggests your adrenal glands aren't responding the way they should, which points toward adrenal insufficiency. This means your body may struggle to handle physical or emotional stress properly. If your results come back low, it's important to seek medical care promptly, since this condition can become serious without proper management.
How often should I retest?
If your first test comes back normal and you're not having symptoms, you likely won't need to retest unless new symptoms appear. If you've been diagnosed with an adrenal condition or started treatment, retesting every few months can help you and your care routine track how well your adrenal glands are responding over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
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Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
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Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Cortisol (Post-ACTH Stimulation) 19 mcg/dL
Demo results
Low (<18 mcg/dL) Optimal (18-25 mcg/dL) High (>25 mcg/dL)
19 mcg/dL

What this means

This value shows how much your cortisol rose after the stimulating injection. A response near the lower end suggests your adrenal glands may not be ramping up cortisol production as well as they should. This pattern is often seen in early or mild adrenal insufficiency and may warrant further evaluation.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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ACTH Stimulation Test for Adrenal Function & Addison's Disease

  • Check adrenal gland stress response
  • Screen for Addison's disease signs
  • Assess unexplained fatigue and weakness
$455
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.