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HMGCR antibody test for muscle weakness or pain from statin use

HMGCR Antibody Test for Statin Muscle Weakness

3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCR) Antibody (IgG)

  • Detect statin-related muscle damage risk
  • Screen unexplained muscle weakness causes
  • Track ongoing muscle pain symptoms
$1201
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're experiencing unexplained muscle weakness, muscle pain, or trouble climbing stairs or lifting your arms, especially if you currently take or have recently taken a statin medication. It helps identify a specific type of muscle damage called necrotizing myopathy that can sometimes develop from statin use. This is useful if your symptoms haven't improved after stopping the statin, since that pattern can point to an ongoing autoimmune reaction rather than a simple drug side effect.

What happens after I get my results?

Your results will show up in your account with a clear explanation of what a normal versus abnormal range means for this antibody. If your result is positive, next steps typically involve looking at muscle enzyme levels and tracking whether symptoms improve or worsen over time, since this can guide decisions about statin use going forward. You can download a standard lab report from your account at any time, and if you retest later you can compare results side by side using the trends feature. If you experience severe or rapidly worsening muscle weakness, seek medical care right away.

Who should consider this test?

Anyone with ongoing muscle weakness or pain that started or worsened after beginning a statin medication should consider this test. It's also useful for people whose muscle symptoms didn't go away after stopping their statin, since that's a signal worth investigating further. People with unexplained high muscle enzyme levels on routine bloodwork may also want to check this.

What symptoms indicate I may need this test?
Common symptoms include progressive muscle weakness, especially in the hips, thighs, shoulders, and upper arms, along with muscle pain or tenderness that doesn't fade over time. Difficulty standing from a seated position, climbing stairs, or raising your arms overhead are also common red flags. These symptoms are worth checking out especially if they appeared or got worse while taking a statin.
How can I naturally support muscle health during recovery?
Gentle, regular movement like walking or light stretching can help maintain muscle function without overloading damaged muscle fibers. Eating enough protein and staying hydrated supports muscle repair, and getting consistent sleep gives your body time to recover. Avoid alcohol and unnecessary muscle strain until you understand what's driving your symptoms, and reintroduce exercise gradually as symptoms improve.
When will I get my results?
Results for this test are typically ready within about 7 days of your sample being collected. You'll be notified as soon as your results are available in your account, where you can view the detailed report and download it whenever you need it.
What is HMGCR antibody myopathy and why does it matter?
HMGCR antibody myopathy is a condition where your immune system mistakenly attacks a muscle protein, causing ongoing muscle breakdown and weakness. It's important because, unlike typical statin muscle aches that go away once you stop the medication, this type of damage can continue or even worsen after stopping the drug. Catching it early with this test can help explain persistent symptoms and guide better management choices.
What does a positive HMGCR antibody result mean?
A positive result means your immune system has produced antibodies that may be attacking a muscle enzyme, which is linked to ongoing muscle damage. This finding, especially paired with muscle weakness or elevated muscle enzymes, suggests an autoimmune muscle condition rather than a typical, temporary statin side effect. It's a signal to track your symptoms closely and consider next steps for managing muscle health.
What causes a positive HMGCR antibody result?
The most common trigger is past or current use of statin medications, which in rare cases can set off an autoimmune reaction against a muscle enzyme. Some people develop this condition even without ever taking a statin, though this is less common. Genetics may also play a role in why some people react this way and others don't.
How often should I retest?
If your first result is positive or your symptoms are ongoing, retesting every few months can help you track whether antibody levels and muscle symptoms are improving or getting worse. If you're symptom-free and just verifying a past concern, a one-time test may be enough. Using the trends feature makes it easy to see your pattern over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
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Fast & confidential, we never sell or share your data
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Demo results
HMGCR Antibody (IgG) Negative
Demo results
Negative (Normal) Positive (Abnormal)
Negative

What this means

A negative result means no significant HMGCR antibodies were detected in your blood, which makes statin-related autoimmune muscle damage unlikely. If you're still having muscle symptoms, other causes may need to be explored.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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HMGCR Antibody Test for Statin Muscle Weakness

  • Detect statin-related muscle damage risk
  • Screen unexplained muscle weakness causes
  • Track ongoing muscle pain symptoms
$1201
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.