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Genetic mutation test for family history of blood clotting disorders

19911A→G Prothrombin Gene Mutation Test

19911A→G Mutation Analysis

  • Assess inherited blood clot risk
  • Screen for prothrombin gene variants
  • Check family history clotting factors
$1510
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're trying to understand your personal risk for blood clots, especially if you already know you carry the G20210A prothrombin mutation. It helps if you have a family history of deep vein thrombosis (DVT) or unexplained blood clotting events and want more clarity on your genetic risk factors. It's also useful for people who've had a clotting event and want to understand whether a genetic factor contributed.

What happens after I get my results?

Your results will show up in your account along with a clear explanation of what a positive or negative finding for this mutation means. If your result suggests an increased clotting risk, practical next steps include discussing lifestyle changes like staying active, avoiding prolonged immobility, and being cautious with certain medications or hormone therapies that raise clotting risk. You can download the standard lab report anytime from your account, and if you ever retest related markers, you'll be able to track those results over time using the trends feature. If you experience sudden leg swelling, pain, or shortness of breath, seek medical care right away.

What symptoms indicate I may need this test?

Signs that might point to a clotting risk worth investigating include a personal or family history of deep vein thrombosis or pulmonary embolism, unexplained leg swelling or pain, or recurrent miscarriages. If a close relative has already tested positive for a prothrombin gene mutation, that's also a strong reason to check your own genetic risk. This test is especially relevant if you already know you carry the G20210A mutation and want to see if the 19911A→G variant modifies your risk further.

How can I naturally support healthy blood flow and clotting balance?
Staying physically active, especially avoiding long periods of sitting or immobility, helps keep blood flowing normally. Drinking enough water, maintaining a healthy weight, and eating a balanced diet with foods low in processed fats can also support healthy circulation. If you travel long distances, taking breaks to walk around and stretch your legs is a simple, effective habit.
When will I get my results?
Results from this genetic test are typically ready within about 7 days of your sample being processed at the lab. You'll get a notification as soon as your results are available in your secure online account. Genetic tests like this one take a bit longer than standard blood work because of the specialized analysis involved.
Who should consider this test?
This test is a good fit for people with a known family history of the G20210A prothrombin mutation or blood clotting disorders. It's also worth considering if you've personally experienced a blood clot without a clear cause, or if you're planning a pregnancy and want to understand inherited clotting risks. People with relatives who've had DVT or pulmonary embolism at a young age may also benefit from this genetic insight.
What is the 19911A→G mutation and why does it matter?
The 19911A→G mutation is a small genetic variation found in the prothrombin (Factor II) gene, which plays a role in how your blood clots. On its own it's considered a mild modifier, but in people who also carry the more well-known G20210A mutation, it may increase or decrease their overall clotting risk. Understanding this variant gives a fuller picture of your inherited clotting risk profile.
What does a positive result for this mutation mean?
A positive result means you carry the 19911A→G variant in your prothrombin gene, which may influence how the G20210A mutation affects your clotting risk. This doesn't mean you will definitely develop a blood clot, but it's useful information to share when making decisions about medications, birth control, hormone therapy, or long surgeries. Practical steps include staying active, avoiding smoking, and being mindful during long periods of inactivity like flights.
How often should I retest for this genetic mutation?
Since this is a genetic test, your result won't change over time, so retesting the same mutation generally isn't necessary. If you're monitoring overall clotting risk, though, you may want to periodically check related markers like clotting factor levels, especially around major life events like pregnancy or surgery. Any future genetic testing would typically focus on other related mutations rather than repeating this one.
What should I do if my results show an increased clotting risk?
If your results suggest an increased risk, focus on lifestyle habits that support healthy circulation, such as regular movement, staying hydrated, and maintaining a healthy weight. Be proactive about mentioning this genetic finding before starting new medications, especially hormonal birth control or hormone replacement therapy, since these can further increase clotting risk. If you notice symptoms like leg swelling, pain, redness, or shortness of breath, seek medical care immediately.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
19911A→G Prothrombin Gene Mutation Negative
Demo results
Negative (Not Detected) Positive (Detected)
Negative

What this means

A negative result means the 19911A→G variant was not found in your prothrombin gene. This suggests this particular genetic factor does not add to any clotting risk you may have from other causes, such as the G20210A mutation.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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19911A→G Prothrombin Gene Mutation Test

  • Assess inherited blood clot risk
  • Screen for prothrombin gene variants
  • Check family history clotting factors
$1510
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.