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Allergy blood test for penicillin sensitivity when skin testing isn't available

Penicillin Allergy Test - Blood Test for Antibiotic Sensitivity

BasoFunction™ HRT Penicillin (Minor Det)

Google
3,138 reviews
  • Pinpoint the cause of your fatigue
  • Reveal hidden allergies affecting you
  • Confirm your hormone balance accurately
First results as soon as overnight*

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We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you've experienced allergic reactions to penicillin or related antibiotics and need confirmation of your sensitivity. It's especially useful when skin testing isn't appropriate for you, such as if you have severe skin conditions, take certain medications, or have had dangerous allergic reactions in the past. Many people use this test to safely determine if they can take penicillin-based antibiotics before medical procedures or treatments.

How should I prepare for this test?

If you're taking calcineurin inhibitors (immunosuppressant medications like tacrolimus or cyclosporine), you'll need to stop these medications 72 hours before your blood draw. This is important because these drugs can affect how your immune cells respond during the test, potentially leading to inaccurate results. Always consult with your prescribing doctor before stopping any medication to ensure it's safe for you.

What's included in this test?

BasoFunction™ HRT Penicillin (Minor Det)

This test measures BasoFunction™ HRT Penicillin (Minor Det), which evaluates how your white blood cells respond when exposed to penicillin in a controlled lab environment. It's an in vitro challenge test that measures histamine release as a marker of allergic cell stimulation, helping confirm whether you have a true allergic sensitivity to penicillin. This test is particularly valuable when traditional skin testing cannot be safely performed or when you need objective confirmation of an allergy.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your test results mean for your antibiotic options and medication safety. These notes include personalized recommendations like which antibiotics to avoid, what information to share with healthcare providers, and whether additional allergy testing may be helpful. You'll also get the standard lab report and can keep these results in your medical records for future reference whenever you need antibiotics.
Who should consider getting this test?
This test is valuable for anyone with a suspected or documented penicillin allergy who cannot undergo skin testing due to severe skin conditions, recent anaphylaxis, or current use of medications that interfere with skin tests. It's also helpful for people who need clarity about their allergy status before surgeries or treatments where penicillin-based antibiotics are preferred. Additionally, it's useful if you've been avoiding penicillin based on childhood reactions but want to confirm whether you still have the allergy.
What symptoms indicate I may need this test?
You may need this test if you've previously experienced hives, swelling, difficulty breathing, or severe rashes after taking penicillin or related antibiotics. Other concerning symptoms include rapid heartbeat, dizziness, gastrointestinal distress, or any reaction that required medical attention after antibiotic use. Even if your reaction was mild, confirming your allergy status helps ensure safe medication choices in the future.
What does a positive result mean?
A positive result indicates that your blood cells showed an allergic response to penicillin in the laboratory setting, confirming you have a sensitivity to this antibiotic. This means you should avoid penicillin and related antibiotics and inform all your healthcare providers about this allergy. Your doctor can recommend alternative antibiotics that are safe for you, and you should consider wearing a medical alert bracelet.
What does a negative result mean?
A negative result suggests that your blood cells did not show an allergic response to penicillin in this test, which may indicate you don't have a true penicillin allergy. However, this test is just one piece of the puzzle, and results should be interpreted by your doctor along with your medical history. In some cases, your doctor may recommend additional testing or a supervised penicillin challenge to fully confirm you can safely take the medication.
Can I outgrow a penicillin allergy?
Yes, many people who had penicillin allergies as children no longer have them as adults. Studies show that up to 80% of people with documented penicillin allergies lose their sensitivity after 10 years. This is why retesting is valuable if you've been avoiding penicillin based on old information, as confirming your current allergy status expands your antibiotic options and can lead to more effective treatments.
What are safe antibiotic alternatives if I'm allergic to penicillin?
If you have a confirmed penicillin allergy, your doctor can prescribe alternative antibiotics like azithromycin, fluoroquinolones (such as levofloxacin), or certain cephalosporins depending on the severity of your allergy and the infection being treated. Some people with penicillin allergies can safely take certain cephalosporin antibiotics, but this should only be determined by your healthcare provider. Always inform every doctor, dentist, and pharmacist about your penicillin allergy to ensure safe medication choices.
How often should I retest for penicillin allergy?
If you test positive for penicillin allergy, there's generally no need for routine retesting unless your doctor recommends it due to changing medical needs or if many years have passed and you want to confirm your current status. However, if you test negative but have a strong history of reactions, your doctor may recommend follow-up testing or supervised challenge in the future. Allergies can change over time, so discussing retesting with your allergist or doctor is worthwhile if your medical situation changes.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
BasoFunction™ HRT Penicillin Negative
Demo results
Negative Positive
Negative

What this means

Your test came back negative, meaning your blood cells did not show an allergic response to penicillin in this controlled test. This suggests you may not have a true penicillin allergy, though your doctor will interpret this result along with your medical history and symptoms.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Penicillin Allergy Test - Blood Test for Antibiotic Sensitivity

Google
3,138 reviews
  • Pinpoint the cause of your fatigue
  • Reveal hidden allergies affecting you
  • Confirm your hormone balance accurately

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.