Call us: 1.877.283.7882 | Monday–Friday: 8:00 AM–4:30 PM ET
Coincident with Ovarian Cancer Awareness Month, the National Cancer Institute is beginning to test a new drug it hopes will more effectively treat types of breast and ovarian cancer.
Dr. Elise Kohn of the Center for Cancer Research will head a clinical trial which tests the effectiveness of the drug AZD2281 in thwarting the repair of mutated genes. The trial is in phase I, which means that safety of the treatment will be the main factor examined.
Prior research has shown that women who have mutations to their BRCA, or tumor suppressor genes, are at a much higher risk of developing breast or ovarian cancer. In the new trial, researchers will administer the new drug and hope that it stunts the capacity of damaged cancer cells to repair themselves.
Kohn summarized the trial stating, "The idea is to stress the cancer cells with [chemotherapy], which is known to be effective in ovarian cancer and possibly some breast cancers, while blocking DNA repair pathways."
Tests on animals have demonstrated that the AZD2281 drug is significantly more toxic to cells with BRCA gene mutations than to cells with normal tumor suppressor genes.
The NCI reports that ovarian cancer testing can help find cancer at an early stage and increase the likelihood that it can be successfully treated.
Related Articles from Private MD:
News Categories:Advanced Lipid Treatment I Allergy Testing Anemia and RBC disorders Autoimmune Diseases Bariatric Lab Testing Blood and Blood Diseases Breast Cancer Detection and Tumor Markers Celiac Disease Testing Chlamydia Coagulation and blood clotting disorders Colon Diabetes DNA, Paternity and Genetic testing Drug Screening Environmental Toxin Testing Female Specific Tests Gastrointestinal Diseases General Health General Wellness Heart Health and Cholesterol Herpes HIV HIV monitoring/Treatment/Testing/Post Diagnos Hormones and Metabolism Infectious Diseases Infertility Testing-Male Infertitlity Hormone Testing Kidney Diseases Leukemia and WBC disorders Liver Liver Diseases Lyme Disease Male Specific Tests Menopause/Peri-Menopausal Diagnosis Musculoskeletal Diseases Organ Specific Testing Ovarian Prostate Sexually Transmitted Diseases Thyroid Diseases Transgender Hormone Testing-female to male Transgender Hormone Testing-Male to Female Vitamin D Deficiency-Diagnosis and Treatment
Visit the Health News Archive: Click Here
Questions about online blood testing or how to order a lab test? Click here to get started or call us toll-free at 1.877.283.7882. Our professionals are ready to assist you.Back to top