What's this test for?

This test is ideal if you're experiencing unexplained fatigue, frequent infections, bone pain, or have been told you have abnormal protein levels in your blood. It helps detect plasma cell disorders like multiple myeloma, which can affect your immune system and bone health. Many people use this test when their doctor suspects an underlying blood or immune condition that needs investigation.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your kappa and lambda light chain levels mean for your immune system health. These notes include personalized recommendations about whether you need follow-up testing, specialist referral, or monitoring over time. You'll also get the standard lab report and can track your light chain levels and ratio over time using our trends feature, which is especially helpful if you're monitoring a known condition.

What's included in this test?

This panel measures Kappa Light Chain Free Serum, Lambda Light Chain Free Serum, and calculates the Kappa/Lambda Light Chains Free With Ratio. This panel measures free kappa and lambda light chains, which are protein fragments produced by plasma cells in your immune system, and calculates the ratio between them. An abnormal ratio can indicate your body is producing too many abnormal plasma cells, which may signal conditions like multiple myeloma, amyloidosis, or other blood disorders. Together, these measurements help identify serious immune system issues that affect your energy levels and overall health.

How should I prepare for this test?

No special preparation is typically required for this test. You can eat and drink normally before your blood draw. However, inform your doctor if you're taking any medications or have received contrast dye recently, as these may affect results in rare cases.

When will I get my results?

Results are typically available within 3-5 business days after your blood sample reaches the laboratory. You'll receive an email notification when your results are ready to view in your secure account, along with easy-to-understand doctor notes explaining what your numbers mean.

Who should consider getting this test?

This test is important for people experiencing bone pain, unexplained fractures, kidney problems, or recurrent infections that suggest an immune system issue. It's also recommended if routine blood work showed abnormal protein levels, anemia, or elevated calcium. Your doctor may order this if they suspect a plasma cell disorder or to monitor a previously diagnosed condition.

What symptoms indicate I may need this test?

Common symptoms include persistent bone pain (especially in the back or ribs), unexplained fatigue that doesn't improve with rest, frequent infections, or unexplained weight loss. You might also experience weakness, numbness or tingling in your legs, excessive thirst, or confusion. If you have these symptoms along with abnormal blood work, this test can help identify the underlying cause.

What does an abnormal kappa/lambda ratio mean?

An abnormal ratio means your body is producing an imbalanced amount of kappa versus lambda light chains, which can indicate abnormal plasma cell activity. A high ratio might suggest your plasma cells are producing too much kappa, while a low ratio suggests too much lambda. This imbalance is a key marker for conditions like multiple myeloma, amyloidosis, or other plasma cell disorders that require medical attention.

What causes abnormal free light chain levels?

Abnormal levels can be caused by plasma cell disorders like multiple myeloma, where cancerous plasma cells overproduce one type of light chain. Other causes include amyloidosis (where light chains form harmful deposits), kidney disease that affects protein filtration, or monoclonal gammopathy of unknown significance (MGUS). Infections, autoimmune diseases, and certain blood cancers can also affect light chain production.

How often should I retest my free light chains?

If you're being monitored for a plasma cell disorder, your doctor will typically retest every 2-3 months to track disease activity and treatment response. For people with MGUS or smoldering myeloma, testing every 6-12 months is common to watch for progression. Your healthcare provider will determine the best schedule based on your specific condition and how stable your levels are.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Immune System Blood Test - Fatigue & Infections

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Blood Test for Fatigue and Immune System Issues

Kappa/Lambda Light Chains, Free with Ratio

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

How should I prepare for this test?

What's included in this test?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Blood Test for Fatigue and Immune System Issues

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say