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HLA typing test for families concerned about autoimmune conditions and transplant compatibility

HLA Genetic Test for Autoimmune Risk and Transplant Matching

HLA DRB3,4,5 Low Resolution

Google
3,138 reviews
  • Pinpoint genetic factors affecting your health
  • Reveal immune system issues effortlessly
  • Clarify potential autoimmune conditions quickly
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're being evaluated for autoimmune conditions, need transplant compatibility screening, or have a family history of immune-related disorders. It identifies specific genetic markers (HLA types) that influence how your immune system functions and responds to threats. Many people use this test when doctors suspect conditions like celiac disease, rheumatoid arthritis, or when determining donor compatibility for organ or bone marrow transplants.

What's included in this test?

HLA DRB3,4,5 Low Resolution

This test measures HLA DRB3, DRB4, and DRB5 genetic markers at low resolution. These specific genes are part of your immune system's identification system and help determine your susceptibility to certain autoimmune diseases and compatibility for transplants. Understanding these markers provides critical information for diagnosing immune-related conditions and assessing whether family members could be suitable transplant donors.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your HLA genetic markers mean for your immune system and disease risk. These notes include personalized guidance on next steps, such as which autoimmune conditions you may have increased susceptibility to or transplant compatibility insights. You'll also get the standard lab report and can track your data over time, which is especially helpful if you're monitoring multiple family members or coordinating with transplant specialists.

Who should consider getting this test?
This test is important for people with suspected autoimmune conditions like celiac disease, type 1 diabetes, or rheumatoid arthritis, as certain HLA types increase risk. It's also essential for anyone needing organ or bone marrow transplant evaluation, both donors and recipients. Family members of transplant candidates often get tested together to find the best donor match.
What are HLA markers and why do they matter?
HLA (Human Leukocyte Antigen) markers are genetic identifiers on your cells that help your immune system distinguish between your own cells and foreign invaders. These markers play a crucial role in autoimmune disease development and transplant compatibility. Certain HLA types are strongly associated with conditions like celiac disease, while matching HLA types between donor and recipient greatly improves transplant success rates.
What symptoms indicate I may need this test?
You might need this test if you experience unexplained chronic fatigue, joint pain, digestive issues, or recurring inflammation that suggests an autoimmune condition. It's also indicated if you have a strong family history of autoimmune diseases or if you're experiencing organ failure requiring transplant evaluation. Your doctor may order this if standard tests haven't identified the cause of your immune-related symptoms.
What does my HLA type tell me about disease risk?
Your HLA type can indicate increased or decreased risk for certain autoimmune conditions, but it doesn't guarantee you'll develop them. For example, certain HLA markers are strongly linked to celiac disease, while others are associated with rheumatoid arthritis or type 1 diabetes. Understanding your HLA profile helps your doctor assess risk and may guide early intervention or monitoring strategies.
How is HLA typing used for transplants?
For transplants, doctors compare HLA types between donors and recipients to find the best match possible. The closer the HLA match, the lower the risk of organ rejection and the better the long-term outcome. Family members, especially siblings, often have better HLA matches than unrelated donors, which is why relatives are frequently tested first when transplant evaluation begins.
Can I reduce my risk if I have high-risk HLA markers?
While you can't change your genetic HLA markers, understanding your risk allows for proactive monitoring and lifestyle adjustments. For celiac disease risk, you can watch for symptoms and get tested if they appear. Maintaining overall immune health through balanced nutrition, stress management, regular exercise, and avoiding smoking can help support healthy immune function regardless of your genetic profile.
How often should I get HLA typing done?
HLA typing is typically a one-time test because your genetic markers don't change throughout your life. Once you know your HLA type, that information remains valid permanently. You may need to share these results with different doctors over time for autoimmune disease evaluation or transplant matching, but you won't need to repeat the actual test.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HLA DRB3 Allele Detected
Demo results
Not Detected Detected
Detected

What this means

Your HLA DRB3 allele was detected through genetic testing. This is simply an identification of your genetic immune markers and provides valuable information about your immune system profile and potential disease associations. Knowing your HLA type helps with autoimmune disease risk assessment and transplant compatibility evaluation.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

HLA Genetic Test for Autoimmune Risk and Transplant Matching

Google
3,138 reviews
  • Pinpoint genetic factors affecting your health
  • Reveal immune system issues effortlessly
  • Clarify potential autoimmune conditions quickly

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.