What's this test for?

This test is ideal if you've experienced severe allergic reactions, unexplained anaphylaxis, or symptoms like flushing, hives, stomach issues, or difficulty breathing that suggest mast cell problems. It helps doctors determine if your mast cells are overactive or if you have conditions like mastocytosis or mast cell activation syndrome. Many people use this test after an allergic emergency or when they have recurring unexplained allergic symptoms.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your tryptase levels mean and how they relate to allergic reactions or mast cell disorders. These notes include personalized recommendations like avoiding specific triggers, when to carry emergency medication like epinephrine, or whether you should see an allergist or immunologist. You'll also get the standard lab report and can track your tryptase levels over time using our trends feature, which is especially helpful for monitoring mast cell conditions.

What's included in this test?

This test measures tryptase, an enzyme released by mast cells during allergic reactions and mast cell activation. Elevated tryptase levels help doctors confirm whether symptoms like severe allergic reactions, anaphylaxis, flushing, or hives are related to mast cell disorders such as mastocytosis or mast cell activation syndrome. The timing of the test is critical, as levels rise during and shortly after mast cell activation events.

How should I prepare for this test?

For the most accurate results, your blood sample should be collected between 15 minutes and 3 hours after the suspected allergic reaction or mast cell activation event. The serum needs to be separated from blood cells within 3 hours of collection. If you're getting a baseline tryptase test (not during a reaction), no special preparation is needed, but discuss timing with your healthcare provider.

Who should consider getting this test?

This test is important for anyone who has experienced severe allergic reactions or anaphylaxis without a clear cause, has recurrent flushing or hives, or has symptoms suggesting mast cell disorders. It's also useful for people with a family history of mastocytosis, those who have had reactions during surgery or to insect stings, and anyone being evaluated for unexplained allergic symptoms. Your doctor may order both a baseline test and one during a reaction for comparison.

What symptoms indicate I may need this test?

Symptoms that may warrant this test include severe allergic reactions or anaphylaxis with unknown triggers, repeated episodes of flushing, hives, or itching, unexplained low blood pressure or fainting, stomach cramping or diarrhea with allergic symptoms, or difficulty breathing during allergic episodes. You may also need this test if you have bone pain, skin lesions that look like freckles, or if allergic symptoms occur with certain foods, medications, or insect stings.

What is tryptase and why does it matter?

Tryptase is an enzyme stored in mast cells, which are immune cells involved in allergic reactions. When mast cells are activated during an allergic reaction, they release tryptase into your bloodstream. Measuring tryptase levels helps doctors confirm whether your symptoms are truly from mast cell activation and can help diagnose conditions like mastocytosis, where too many mast cells accumulate in your body. Elevated baseline levels can also indicate you're at higher risk for severe reactions.

What does high tryptase mean?

High tryptase levels during or shortly after symptoms suggest active mast cell activation, confirming that your reaction was caused by mast cells releasing their contents. Persistently elevated baseline tryptase may indicate mastocytosis or another mast cell disorder. Temporary elevations are normal during allergic reactions, but if your baseline level is high when you're feeling well, it warrants further investigation by an allergist or immunologist.

How can I manage mast cell activation?

Managing mast cell issues involves identifying and avoiding your specific triggers, which may include certain foods, medications, temperature changes, stress, or physical pressure. Antihistamines can help control symptoms, and your doctor may prescribe mast cell stabilizers. Carrying an epinephrine auto-injector is crucial if you've had severe reactions. Keeping a symptom diary can help you identify patterns and triggers to avoid.

How often should I retest tryptase?

If you've had a reaction, your doctor will typically order one test during or shortly after the event and another baseline test when you're feeling well for comparison. If you're diagnosed with a mast cell disorder, retesting frequency depends on your condition and treatment, but it's often monitored every 6-12 months. Your allergist will guide you on the appropriate testing schedule based on your symptoms and how well your condition is controlled.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Tryptase Test - Allergic Reactions & Mast Cell Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Blood Test for Allergic Reactions and Mast Cell Disorders

Tryptase

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

How should I prepare for this test?

What's included in this test?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Blood Test for Allergic Reactions and Mast Cell Disorders

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say