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T-cell clonality PCR test for suspected T-cell malignancy or cancer monitoring

T-Cell Clonality Test for Lymphoma & Leukemia Evaluation

T-cell Clonality Panel (TCRB, TCRG), PCR

  • Screen for T-cell cancer markers
  • Detect abnormal immune cell growth
  • Monitor cancer treatment recovery progress
$3866
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if you're being evaluated for a possible T-cell malignancy, such as a T-cell lymphoma or leukemia, or if you're being monitored for residual disease after treatment. It looks for a specific genetic pattern that shows whether T-cells in your body are growing from a single abnormal source (clonal) rather than a normal, diverse population. This is typically used alongside other clinical findings to help identify or track T-cell cancers.

What's included in this test?

This test uses a PCR method to examine two different genetic regions on your T-cells (the T-cell receptor beta and gamma genes). Looking at both of these regions together allows for a very high detection rate of abnormal clonal T-cell populations, which is why this combined approach is considered more thorough than checking just one region alone.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a clonal versus non-clonal (polyclonal) finding means. If the result shows a clonal population, this is generally something that needs prompt follow-up given the seriousness of the possible underlying conditions, so seeking medical care quickly is recommended. You can download a standard lab report from your account at any time, and if you're being monitored over time for residual disease, you can track sequential results using the trends feature.

How can I naturally support immune health?
While this test looks at a genetic pattern that can't be changed with lifestyle habits, supporting your overall immune system is still valuable. Eating a balanced diet with plenty of fruits, vegetables, and lean protein, getting regular sleep, managing stress, and staying active all help your immune system function well. These habits don't replace medical follow-up if a concerning result comes back, but they support your overall health during any evaluation or monitoring process.
When will I get my results?
Results are typically available within about 7 days after your sample is processed at the lab. This test involves specialized PCR-based genetic analysis, which takes longer than routine bloodwork, so the turnaround reflects the complexity of interpreting T-cell receptor gene patterns.
Who should consider this test?
This test is generally considered for people who have signs or findings that suggest a possible T-cell cancer, such as unexplained swollen lymph nodes, skin lesions, or abnormal blood cell counts. It's also useful for people who have already been treated for a T-cell malignancy and need to check for residual or returning disease. This isn't a routine screening test for the general population — it's typically used in more specific situations.
What symptoms might suggest I need this test?
Symptoms that sometimes lead to this kind of testing include persistent swollen lymph nodes, unexplained skin rashes or lesions that don't resolve, unexplained fevers, night sweats, or unintentional weight loss. Abnormal results on a routine blood count can also prompt further evaluation with this type of test. These symptoms have many possible causes, so this test helps narrow down whether a T-cell malignancy could be involved.
What does a clonal result mean?
A clonal result means that a large portion of your T-cells appear to have come from the same original cell, which can be a sign of an abnormal, potentially cancerous growth pattern. This finding on its own doesn't confirm a diagnosis, but it's a significant flag that typically calls for prompt further evaluation. If you get this result, seeking medical care quickly is the right next step.
What does a non-clonal (polyclonal) result mean?
A polyclonal, or non-clonal, result means your T-cells show a normal, diverse genetic pattern, which is what's typically seen in healthy immune systems fighting off infections or reacting to inflammation. This is generally a reassuring finding when a T-cell malignancy is being considered. However, if your symptoms continue, further evaluation may still be appropriate.
How often should I retest?
If you're being monitored for residual disease after treatment for a T-cell malignancy, retesting is typically done on a schedule tied to your treatment and monitoring plan, often every few months. If this is a one-time diagnostic test, retesting usually isn't needed unless new symptoms develop. Using the trends feature in your account can help you and anyone reviewing your case see how your results change over time.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Get lab order in minutes, results come overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
T-cell Clonality (TCRB/TCRG) Polyclonal (Negative)
Demo results
Polyclonal (Normal) Clonal (Abnormal)
Polyclonal (Negative)

What this means

A polyclonal result means your T-cells show a normal, diverse genetic pattern with no evidence of a single abnormal cell line dominating. This is a reassuring finding when a T-cell malignancy is being considered. A clonal result, by contrast, suggests an abnormal population that typically needs prompt follow-up.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Find a lab near you

Search Quest Diagnostics and LabCorp locations available through Private MD Labs.

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T-Cell Clonality Test for Lymphoma & Leukemia Evaluation

  • Screen for T-cell cancer markers
  • Detect abnormal immune cell growth
  • Monitor cancer treatment recovery progress
$3866
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.