What's this test for?

This test is ideal if you're concerned about a family history of rhabdoid tumors or a rare ovarian cancer called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). It helps if you have relatives diagnosed with these cancers at a young age or if a family member already tested positive for a SMARCA4 gene change. Knowing your genetic status can help you understand your own cancer risk and plan next steps.

What's included in this test?

This test looks closely at the entire SMARCA4 gene using two methods together: sequencing, which reads the gene's code letter by letter to find small changes, and deletion/duplication analysis, which checks for missing or extra pieces of the gene. Using both methods gives a more complete picture, since some genetic changes are only caught by one method or the other.

What happens after I get my results?

Your results will be available in your secure online account, with a clear explanation of what your result means and how it compares to normal findings. If a pathogenic change is found, next steps typically include increased cancer screening and sharing the result with blood relatives so they can consider testing too. You can download the full lab report from your account at any time, and the trends feature lets you keep a record of this result alongside any future testing.

How can I naturally support my overall cancer risk management?

While no lifestyle change can undo a genetic risk, staying at a healthy weight, avoiding tobacco, limiting alcohol, and eating a diet rich in vegetables and fiber can support your body's natural defenses. Regular physical activity and good sleep also help your immune system function well. These habits work best alongside recommended cancer screenings, not as a replacement for them.

When will I get my results?

Results are typically ready within about 7 days after your sample is received by the lab. This turnaround allows enough time for both the detailed sequencing and deletion/duplication portions of the analysis to be completed carefully. You'll receive a notification as soon as your report is available in your account.

Who should consider this test?

This test is a good fit for people with a personal or family history of rhabdoid tumors, SCCOHT (a rare ovarian cancer), or a known SMARCA4 gene change in the family. It's also worth considering if a relative was diagnosed with an unusual or early-onset cancer and the cause hasn't been identified. Talking through your family's cancer history can help you decide if this test makes sense for you.

What symptoms or history suggest I may need this test?

Warning signs include a family history of rhabdoid tumors (often diagnosed in infants or young children) or a diagnosis of small cell carcinoma of the ovary, hypercalcemic type, which tends to occur in younger women. Multiple relatives with rare or early-onset cancers can also be a signal. This test is about identifying inherited risk rather than diagnosing current symptoms.

What is rhabdoid tumor predisposition syndrome and why does it matter?

Rhabdoid tumor predisposition syndrome 2 is an inherited condition caused by changes in the SMARCA4 gene that raises the risk of developing certain rare, aggressive tumors. It matters because knowing you carry this gene change allows for earlier and more frequent cancer screening, which can catch tumors sooner when they're easier to treat. It also helps other family members understand their own risk.

What does a positive (pathogenic) result mean?

A positive result means a harmful change was found in your SMARCA4 gene, which raises your lifetime risk of rhabdoid tumors or SCCOHT compared to the general population. It does not mean you will definitely develop cancer, but it does mean closer monitoring is recommended. This information can also guide testing decisions for your children, siblings, and parents.

What should I do if my results show a gene change?

If your results show a pathogenic SMARCA4 change, the recommended next step is to set up a personalized cancer screening schedule so any tumors can be caught early. Sharing the result with close biological relatives is also important, since they may carry the same change and benefit from testing. Keeping a copy of your report handy for any future health visits is a good practice.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

SMARCA4 Gene Test - Rhabdoid Tumor & SCCOHT Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

SMARCA4 Gene Test for Rhabdoid Tumor Cancer Risk

SMARCA4 Sequencing and Deletion/Duplication

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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SMARCA4 Gene Test for Rhabdoid Tumor Cancer Risk

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

1,000,000+ blood tests later, here's what our customers say