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Meconium opiate confirmation test for newborns with suspected in utero opioid exposure

Opiate Confirmation Test — Meconium Newborn Screening

Opiate, Confirmation, Meconium

  • Confirm newborn opioid exposure accurately
  • Detect five specific prescription opioids
  • Screen meconium for prenatal drug exposure
$505
First results as soon as overnight*

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

Prescription & all lab fees included

Go directly to the lab, no extra fees

Doctor's guidance included

Easy to understand results

Fast & convenient

Lab visit as quick as 10 mins in & out

All results normal? Get your money back. First-time customers only. File a support ticket titled “Money Back Guarantee” with your order number within 15 days of receiving your results. STD, Sickle Cell, and gift orders aren’t eligible. Full terms apply. guarantee
No questions asked refunds
LegitScript certified

What's this test for?

This test is ideal if there's a concern that a newborn may have been exposed to opioids before birth. It confirms whether specific opioids like codeine, morphine, hydrocodone, hydromorphone, or oxycodone were present during pregnancy by analyzing the baby's first stool (meconium). It's often used when maternal drug history is unclear or when a newborn shows signs that could be related to opioid withdrawal.

How should I prepare for this test?

How can meconium naturally clear opioid traces over time? Meconium itself isn't something you can influence once formed, since it accumulates passively during the last trimester of pregnancy. The best way to support a newborn's recovery from opioid exposure is calm, low-stimulation care, frequent small feedings, skin-to-skin contact, and close monitoring for withdrawal signs. Reducing or stopping opioid use during pregnancy under proper guidance is the only way to lower the amount that accumulates in meconium.

What's included in this test?

This panel checks meconium for five specific opioids and their metabolites using a highly accurate lab method called gas chromatography/mass spectrometry. Testing multiple opioids matters because each one can come from different sources (prescription pain medication, illicit drug use, or breastfeeding exposure), and identifying the specific substance helps guide appropriate newborn care. Note that this test does not detect fentanyl, so a negative result doesn't rule out fentanyl exposure.

What happens after I get my results?
Your results will appear in your account, with each opioid listed along with its cutoff value so you can see exactly what a positive or negative result means. If any opioid is detected at or above the cutoff, the next step is typically closer monitoring of the newborn for withdrawal symptoms and follow-up care planning. A downloadable lab report is available in your account for your records, and you can revisit results anytime, though this is typically a one-time confirmatory test rather than one you'd track over time.
When will I get my results?
Results are typically ready within about 7 days of the lab receiving the meconium sample. Because this test uses a detailed confirmatory method, it takes a bit longer than a basic screening test, but it provides more definitive answers about which specific opioids were present.
Who should consider this test?
This test is generally considered for newborns when there's reason to suspect opioid exposure during pregnancy, such as unclear or inconsistent maternal drug history, or when a baby shows symptoms suggestive of withdrawal. It may also be used when the American Academy of Pediatrics guidance recommends meconium testing over urine or umbilical cord samples due to its ability to reflect exposure over a longer window.
What symptoms indicate I may need this test?
In newborns, signs like excessive crying, trouble feeding, tremors, poor sleep, sweating, or difficulty being consoled can be linked to neonatal opioid withdrawal syndrome. Low birthweight or preterm birth combined with a known or suspected history of maternal opioid use are also reasons this test might be recommended. These symptoms alone don't confirm exposure, which is why lab confirmation through meconium testing is useful.
What does a positive result mean?
A positive result means the specific opioid was found in the meconium at or above the cutoff level, confirming that the baby was exposed to that opioid before birth. This information helps guide appropriate monitoring and supportive care for the newborn since symptoms of withdrawal can vary depending on which opioid was involved. It should always be considered alongside the family history and physical exam findings for the fullest picture.
What does a negative result mean?
A negative result means none of the tested opioids were found above the cutoff level in the meconium sample. However, a negative result does not completely rule out in utero opioid exposure, since how often the opioid was used during pregnancy can affect whether it shows up in meconium. This test also doesn't screen for fentanyl, so a negative result doesn't rule out exposure to that specific drug.
What should happen if results are abnormal?
If an opioid is confirmed in the meconium, the next step is typically close monitoring of the newborn for withdrawal symptoms like tremors, feeding difficulty, or excessive irritability. Supportive care such as swaddling, dim lighting, frequent small feeds, and skin-to-skin contact can help manage mild symptoms. If withdrawal symptoms become severe, such as continuous vomiting, high fever, or seizures, seek medical care right away.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
Opiates (Meconium Confirmation Panel) Negative
Demo results
Negative Positive
Negative

What this means

A negative result means none of the tested opioids (codeine, morphine, hydrocodone, hydromorphone, oxycodone) were found above the cutoff level in the meconium sample. This suggests no confirmed in utero exposure to these specific opioids, though it does not rule out exposure to fentanyl or infrequent opioid use that may not have accumulated enough to detect.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
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Opiate Confirmation Test — Meconium Newborn Screening

  • Confirm newborn opioid exposure accurately
  • Detect five specific prescription opioids
  • Screen meconium for prenatal drug exposure
$505
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.