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Autoimmune Liver Antibody Test for Fatigue and Jaundice

Mitochondria M2 Antibody (IgG), EIA

  • Checks for liver-related antibodies
  • Detects autoimmune liver disease markers
  • Identifies liver cell damage indicators
$402
First results as soon as overnight*

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Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

Sample health report with biomarker results, insights, and recommendations See what you get

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, abdominal discomfort, jaundice (yellowing of skin or eyes), or abnormal liver enzyme results that suggest possible autoimmune liver disease. It helps detect specific antibodies that indicate your immune system may be attacking your liver cells, which is common in conditions like primary biliary cholangitis. Many people use this test when their doctor suspects an autoimmune component to their liver problems but needs confirmation.

What's included in this test?

This test measures Mitochondria M2 Antibody (IgG), which is a specific marker associated with autoimmune liver conditions, particularly primary biliary cholangitis. Detecting this antibody helps identify whether your immune system is producing proteins that attack the mitochondria in liver cells, causing inflammation and potential damage. This measurement is crucial for diagnosing autoimmune liver disease early and distinguishing it from other causes of liver dysfunction.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your antibody levels mean for your liver health and whether autoimmune activity is detected. These notes include personalized recommendations like dietary changes to support liver function, when to follow up with a hepatologist or gastroenterologist, and lifestyle adjustments to protect your liver. You'll also get the standard lab report and can track your antibody levels over time using our trends feature to monitor disease progression or response to treatment.

Who should consider getting this test?
This test is important for people with unexplained abnormal liver function tests, chronic fatigue, or itching without an obvious cause. It's especially relevant for middle-aged women, as autoimmune liver diseases like primary biliary cholangitis are more common in this group. Anyone with a family history of autoimmune conditions or those experiencing symptoms like jaundice, dark urine, or persistent abdominal discomfort should also consider this test.
What symptoms indicate I may need this test?
Key symptoms include persistent fatigue that doesn't improve with rest, unexplained itching (especially at night), yellowing of the skin or eyes, dark-colored urine, and pain or discomfort in the upper right abdomen. You might also experience loss of appetite, unexplained weight loss, or notice unusual bruising. If you've had abnormal liver enzyme results on routine blood work without a clear cause, this test can help determine if autoimmune activity is involved.
How can I naturally support my liver health?
Supporting liver health involves limiting alcohol consumption or avoiding it completely, maintaining a healthy weight through balanced nutrition and regular exercise, and staying hydrated throughout the day. Include liver-friendly foods like leafy greens, cruciferous vegetables (broccoli, cauliflower), berries, and fatty fish rich in omega-3s. Avoid excessive use of over-the-counter pain medications, manage stress through relaxation techniques, and ensure adequate sleep to allow your liver time to repair and regenerate.
What is primary biliary cholangitis and why does it matter?
Primary biliary cholangitis (PBC) is an autoimmune disease where your immune system mistakenly attacks the small bile ducts in your liver, causing inflammation and scarring over time. This damage can interfere with your liver's ability to remove toxins and produce bile for digestion, potentially leading to cirrhosis if untreated. Early detection through antibody testing like this one is crucial because treatment can slow disease progression and significantly improve quality of life and long-term outcomes.
What does a positive result mean?
A positive result means that Mitochondria M2 antibodies were detected in your blood, which strongly suggests the presence of an autoimmune liver condition, most commonly primary biliary cholangitis. This doesn't necessarily mean severe disease, as many people are diagnosed early and manage the condition effectively with medication. Your doctor will use this result along with other tests and symptoms to confirm the diagnosis and develop an appropriate treatment plan.
What does a negative result mean?
A negative result means no Mitochondria M2 antibodies were detected, making primary biliary cholangitis less likely as the cause of your symptoms. However, a negative result doesn't completely rule out autoimmune liver disease, as some people with the condition may not have detectable levels of this specific antibody. Your doctor may recommend additional testing or consider other causes for your liver-related symptoms or abnormal liver function.
How often should I retest if I have autoimmune liver disease?
If you've been diagnosed with autoimmune liver disease, your doctor will typically monitor your condition every 3-6 months initially to assess disease activity and treatment effectiveness. Once your condition is stable, testing frequency may decrease to every 6-12 months. The exact timing depends on your disease severity, symptoms, treatment response, and other liver function markers your doctor is tracking alongside this antibody test.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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Save a trip to the doctor, go directly to the lab
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Results explained in simple language
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Fast & confidential, we never sell or share your data
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* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More advanced tests may take longer due to complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

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Autoimmune Liver Antibody Test for Fatigue and Jaundice

  • Checks for liver-related antibodies
  • Detects autoimmune liver disease markers
  • Identifies liver cell damage indicators
$402
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
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For informational purposes only. Not medical advice.