What's this test for?

This test is ideal if you're experiencing symptoms like unexplained high blood pressure, rapid heartbeat, severe headaches, excessive sweating, or anxiety attacks. It helps detect tumors of the adrenal glands (like pheochromocytomas) that produce too much stress hormones, and monitors how well your adrenal glands are functioning. Many people use this test when they have blood pressure that's hard to control or episodes of feeling like their heart is racing for no clear reason.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your metanephrine levels mean for your adrenal health and blood pressure. These notes include personalized recommendations like whether you need imaging studies, specialist follow-up, or medication adjustments. You'll also get the standard lab report and can track your metanephrine levels over time using our trends feature, which is especially helpful if you're monitoring for adrenal tumors or managing treatment.

What's included in this test?

This test measures fractionated metanephrines including metanephrine and normetanephrine using advanced LC/MS/MS technology in urine collected over 24 hours. This test uses advanced LC/MS/MS technology to measure fractionated metanephrines (metanephrine and normetanephrine) in your urine collected over 24 hours. These are breakdown products of adrenaline and noradrenaline, the stress hormones produced by your adrenal glands. Elevated levels can indicate adrenal tumors or excessive stress hormone production, which helps explain symptoms like uncontrolled blood pressure, heart palpitations, and anxiety episodes.

How should I prepare for this test?

You'll need to collect all your urine over a full 24-hour period in a special container. During the collection period, avoid certain foods and medications that can interfere with results - your lab will provide specific instructions about avoiding caffeine, certain fruits like bananas, and some medications. It's important to follow the collection instructions carefully and keep the specimen refrigerated during the collection period.

Who should consider getting this test?

This test is important for anyone with hard-to-control high blood pressure, especially if it comes in episodes or spikes suddenly. It's also recommended if you experience the classic trio of symptoms: severe headaches, excessive sweating, and rapid heartbeat. People with a family history of adrenal tumors or those being monitored after treatment for pheochromocytoma should also consider regular testing.

What symptoms indicate I may need this test?

Key symptoms include sudden episodes of high blood pressure accompanied by headaches, sweating, and a pounding heartbeat. You might also experience tremors, anxiety or panic attacks, pale skin, nausea, or unexplained weight loss. These episodes can be triggered by stress, certain foods, or physical activity, and may last from a few minutes to several hours.

What are metanephrines and why do they matter?

Metanephrines are the breakdown products of adrenaline and noradrenaline, the hormones your body releases during stress or danger (the fight-or-flight response). When these levels are too high, it can indicate a tumor on your adrenal glands that's overproducing these hormones. This matters because these tumors can cause dangerously high blood pressure, heart problems, and other serious complications if left untreated.

What does high metanephrine mean?

High metanephrine levels often suggest a pheochromocytoma or paraganglioma - rare tumors that produce excess stress hormones. This causes your body to act like it's constantly in a state of emergency, leading to high blood pressure, rapid heartbeat, and other symptoms. If your levels are elevated, your doctor will likely recommend imaging tests to locate any tumors and discuss treatment options, which often involve surgical removal.

How can I naturally support healthy adrenal function?

While you cannot treat adrenal tumors naturally, you can support overall adrenal health through stress management techniques like meditation, deep breathing, and adequate sleep. Regular moderate exercise, a balanced diet rich in whole foods, and avoiding excessive caffeine and alcohol can help. However, if you have elevated metanephrines indicating a tumor, medical treatment is necessary - natural approaches alone are not sufficient.

How often should I retest my metanephrine levels?

If you're being evaluated for a suspected adrenal tumor, your doctor may retest after imaging or before surgery. After surgical removal of a pheochromocytoma, you'll typically be retested at 2-6 weeks post-surgery, then periodically (often annually) for several years to monitor for recurrence. If your initial test was normal but symptoms persist, your doctor may recommend retesting in a few months or testing during a symptomatic episode.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Stress Hormone Test - High Blood Pressure Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Urine Test for High Blood Pressure and Adrenal Health

Metanephrines, Fractionated, LC/MS/MS, 24-Hour Urine

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

How should I prepare for this test?

What's included in this test?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Urine Test for High Blood Pressure and Adrenal Health

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say