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Lynch Syndrome genetic testing for families with hereditary colon cancer risk

Genetic Test for Colon Cancer Risk and Family History

Lynch Syndrome Panel

Google
3,138 reviews
  • Checks genetic risk for colon cancer
  • Identifies inherited cancer-causing genes
  • Detects genetic mutations linked to cancer
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you have a strong family history of colon, uterine, or other digestive cancers, or if you've been diagnosed with colon cancer at a young age. It identifies inherited genetic mutations that significantly increase your risk for certain cancers, allowing you to take proactive steps for early detection and prevention. Many people use this test when multiple family members have had cancer or when their doctor suspects a hereditary cancer syndrome.

What's included in this test?

This panel analyzes the major genes associated with Lynch Syndrome, including MLH1, MSH2, MSH6, PMS2, and EPCAM, which are responsible for repairing DNA damage in your cells. When these genes have mutations, your body's ability to fix DNA errors is impaired, dramatically increasing the risk of colon, uterine, ovarian, stomach, and other cancers. This comprehensive genetic analysis provides crucial information for you and your family members about inherited cancer risk and helps doctors create a personalized screening and prevention plan.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your genetic findings mean for your cancer risk and what screening steps you should consider. These notes include personalized recommendations like enhanced surveillance schedules, preventive measures, and whether genetic counseling or consultation with an oncologist would be beneficial. You'll also get the standard lab report, and this baseline genetic information helps guide your long-term health monitoring and screening strategy.

Who should consider getting this test?
This test is essential for anyone with a personal history of colon or uterine cancer before age 50, or anyone with multiple family members who've had Lynch-related cancers. It's also recommended if you have colon polyps at a young age, multiple colon cancers, or if a family member has already tested positive for Lynch Syndrome. Knowing your status helps you and your relatives make informed decisions about cancer screening and prevention.
What symptoms indicate I may need this test?
While Lynch Syndrome itself doesn't cause symptoms, warning signs include a family pattern of colon, uterine, ovarian, or stomach cancers, especially when diagnosed before age 50. Other indicators include having multiple relatives on the same side of the family with these cancers, developing colon polyps at a young age, or having more than one type of Lynch-related cancer yourself. If these patterns exist in your family, genetic testing can provide important answers.
What does a positive result mean?
A positive result means you have a mutation in one of the Lynch Syndrome genes, which significantly increases your lifetime risk for certain cancers, particularly colon and uterine cancer. However, this doesn't mean you'll definitely develop cancer—it means you need enhanced screening and preventive measures. With regular colonoscopies starting in your 20s or 30s and other surveillance, many cancers can be prevented or caught early when they're most treatable.
What should my family know about my results?
If you test positive for Lynch Syndrome, your blood relatives (parents, siblings, children) have a 50% chance of having the same mutation and should consider genetic testing. This information can be life-saving for your family members, as it allows them to start early screening and prevention strategies. Genetic counseling can help you understand how to share this information sensitively and what it means for your family's health planning.
How can I reduce my cancer risk if I have Lynch Syndrome?
Regular colonoscopies every 1-2 years starting in your 20s or 30s are crucial for catching and removing precancerous polyps before they become dangerous. Women should have annual screenings for uterine and ovarian cancer or consider preventive surgery after childbearing. Maintaining a healthy weight, exercising regularly, eating plenty of fiber, limiting red meat, and avoiding smoking can also help reduce cancer risk. Some people also discuss aspirin therapy with their doctor for additional protection.
What is Lynch Syndrome and why does it matter?
Lynch Syndrome is the most common inherited cause of colon cancer, affecting about 1 in 300 people. It's caused by mutations in genes that normally repair DNA mistakes in your cells. When these repair genes don't work properly, errors accumulate and can lead to cancer, particularly in the colon, uterus, ovaries, and stomach. Knowing you have Lynch Syndrome allows you to be proactive with screening and prevention, dramatically improving your chances of catching cancer early or preventing it altogether.
How often should I get screened if I have Lynch Syndrome?
If you test positive, you'll typically need a colonoscopy every 1-2 years starting at age 20-25 or 2-5 years before the youngest cancer diagnosis in your family, whichever is earlier. Women should have annual screening for uterine and ovarian cancer starting at age 30-35. Your healthcare team will create a personalized surveillance schedule based on your specific mutation, family history, and individual risk factors. Regular screening is key to catching any problems early.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
MLH1 Gene Mutation Not Detected
Demo results
Not Detected Detected
Not Detected

What this means

Your test came back negative, meaning no mutations were detected in the MLH1 gene. This is the expected and healthy result, indicating you do not have this particular genetic mutation associated with Lynch Syndrome.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Genetic Test for Colon Cancer Risk and Family History

Google
3,138 reviews
  • Checks genetic risk for colon cancer
  • Identifies inherited cancer-causing genes
  • Detects genetic mutations linked to cancer

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.