What's this test for?

This test is ideal if you're experiencing a personal or family history of colorectal cancer, especially if it developed at a younger age or has shown up across multiple generations. It's also useful if a prior tumor test showed microsatellite instability (MSI), a pattern linked to Lynch syndrome. This test looks for changes in the MSH6 gene that can raise your risk of colorectal and other cancers, so you and your family can plan ahead with more information.

What's included in this test?

This test combines two methods to look closely at the MSH6 gene: one that reads through the gene's code letter by letter, and one that checks for missing or duplicated sections of the gene. Together they help catch a wide range of genetic changes that could explain a personal or family pattern of colorectal cancer. Each method has different strengths, which is why combining them gives a more complete picture than either alone.

What happens after I get my results?

Your results will be available in your account, with an explanation of what a positive or negative finding means for the MSH6 gene. If a mutation is found, next steps typically include more frequent cancer screening and sharing the information with blood relatives who may also want to get tested. The full lab report can be downloaded directly from your account, and because this is a one-time genetic result, there's no need for retesting, though you can keep the report on file and refer back to it anytime through your account.

How can I naturally support colon health?

While no lifestyle change can undo a genetic mutation, everyday habits can support your colon health and lower overall cancer risk. Eating more fiber-rich foods like vegetables, fruits, and whole grains, cutting back on red and processed meats, staying active, and avoiding smoking and heavy drinking all help. Regular screening, such as colonoscopies at intervals suited to your risk level, remains the most effective way to catch problems early.

When will I get my results?

Results are typically ready within about 7 days of your sample being received at the lab. Because this is a detailed genetic analysis, it takes a bit longer than routine blood work. You'll be notified as soon as your results are posted to your account.

Who should consider this test?

This test is a good fit for people with a personal history of colorectal cancer that meets specific risk criteria, or those with close relatives who have had colorectal or related cancers at a young age. It's also worth considering if a family member has already been diagnosed with a mismatch repair gene mutation. Talking through your family cancer history can help you decide if this test makes sense for you.

What symptoms or history suggest I may need this test?

Because Lynch syndrome doesn't cause everyday symptoms on its own, the signals to watch for are usually in your personal or family history rather than physical symptoms. These include colorectal cancer diagnosed before age 50, multiple family members with colorectal or endometrial cancer, or a tumor that previously tested positive for microsatellite instability. If any of these apply to you or your close relatives, this test can provide useful answers.

What is Lynch syndrome and why does it matter?

Lynch syndrome is an inherited condition caused by changes in genes, including MSH6, that normally help repair small errors in your DNA. When these genes don't work properly, errors can build up over time and increase the chance of developing colorectal, endometrial, and certain other cancers. Knowing you carry a related gene change matters because it allows for earlier and more frequent cancer screening, which can catch problems before they become serious.

What does a positive result mean?

A positive result means a mutation was found in the MSH6 gene, which raises your lifetime risk of colorectal and certain other cancers compared to the general population. It does not mean you have cancer now or definitely will develop it, but it does mean earlier and more frequent screening is a smart move. Sharing this result with blood relatives is also important, since they may carry the same mutation and benefit from testing too.

What should I do if my results show a mutation?

If a mutation is found, the most useful next step is increasing how often you get screened for colorectal cancer, often starting earlier and repeating more frequently than standard guidelines suggest. It's also worth letting close family members know, since they may want to get tested themselves. If you experience new or concerning symptoms like unexplained bleeding, persistent abdominal pain, or unexplained weight loss, seek medical care promptly.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Lynch Syndrome MSH6 Test - Colorectal Cancer Risk

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Lynch Syndrome MSH6 Gene Test for Colorectal Cancer Risk

Lynch Syndrome, MSH6 Sequencing and Deletion/Duplication

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

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Lynch Syndrome MSH6 Gene Test for Colorectal Cancer Risk

Prescription & all lab fees included

Doctor's guidance included

Fast & convenient

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