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Lupus antibody screening for families concerned about autoimmune symptoms and inflammatory conditions

Blood Test for Joint Pain, Fatigue, and Lupus Symptoms

Lupus Panel 3 with ANA, IFA with Reflex to Titer and Pattern

Google
3,141 reviews
  • Checks for lupus-related antibodies
  • Identifies autoimmune disease indicators
  • Analyzes blood for lupus markers
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained joint pain, persistent fatigue, skin rashes (especially a butterfly-shaped rash on your face), recurring fevers, or unusual sensitivity to sunlight. It helps identify lupus and other autoimmune disorders by detecting specific antibodies your immune system produces when it mistakenly attacks your own tissues. Many people use this test when they have concerning symptoms that suggest an autoimmune condition but need concrete answers to guide treatment.

How should I prepare for this test?

No special preparation is typically required for this test. You don't need to fast, and you can take your regular medications unless your doctor advises otherwise. It's best to schedule your test at a time when you're experiencing typical symptoms if possible, and inform your healthcare provider about any medications you're taking, as some can affect ANA results.

What's included in this test?

This panel uses a specialized immunofluorescence assay (IFA) to detect antinuclear antibodies (ANA), which are markers your immune system creates when it attacks your own cells. If ANA is detected, the test automatically reflexes to determine the specific titer (concentration) and pattern, providing crucial information about what type of autoimmune activity may be present. Together, these measurements help distinguish lupus from other autoimmune conditions and assess disease severity.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your antibody levels mean and whether they indicate lupus or other autoimmune activity. These notes include personalized recommendations about lifestyle modifications, symptom management strategies, and whether you should follow up with a rheumatologist for specialized care. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially helpful for monitoring disease activity if you're diagnosed.
Who should consider getting this test?
This test is important for anyone experiencing classic lupus symptoms like unexplained joint pain and swelling, extreme fatigue, skin rashes, or sensitivity to sunlight. It's also valuable for people with a family history of lupus or autoimmune diseases, women of childbearing age with unexplained symptoms (as lupus predominantly affects women), and anyone whose doctor suspects an autoimmune condition based on their symptoms and medical history.
What symptoms indicate I may need this test?
Common symptoms that suggest you may need lupus testing include persistent joint pain or swelling (especially in hands, wrists, and knees), extreme fatigue that doesn't improve with rest, a butterfly-shaped rash across your cheeks and nose, fever without infection, unusual hair loss, mouth sores, chest pain when breathing deeply, fingers turning white or blue in cold (Raynaud's phenomenon), or unexplained swelling in legs or around eyes. If you're experiencing several of these symptoms together, this test can help identify the underlying cause.
How can I naturally support my immune system with lupus?
Managing lupus involves protecting yourself from sun exposure by wearing sunscreen (SPF 50+), protective clothing, and avoiding peak sun hours, as UV light can trigger flares. Getting adequate rest (7-9 hours nightly), managing stress through meditation or gentle yoga, and eating an anti-inflammatory diet rich in omega-3 fatty acids (fish, flaxseed), colorful fruits, and vegetables can help reduce symptoms. Regular low-impact exercise like swimming or walking, avoiding smoking, and limiting alcohol can also help manage inflammation and maintain overall health.
What is ANA and why does it matter?
ANA stands for antinuclear antibodies, which are proteins your immune system creates when it mistakenly targets the nucleus (control center) of your own cells. While ANA can be present in healthy people at low levels, higher concentrations or specific patterns are strongly associated with lupus and other autoimmune diseases like rheumatoid arthritis or Sjögren's syndrome. The titer (concentration) and pattern of ANA help doctors determine whether an autoimmune condition is present and guide appropriate treatment.
What does a positive ANA test mean?
A positive ANA test means that antinuclear antibodies were detected in your blood, indicating your immune system is producing antibodies against your own cells. However, a positive ANA doesn't automatically mean you have lupus—it can occur in other autoimmune conditions, certain infections, or even in some healthy individuals. The specific titer level and pattern, combined with your symptoms and other test results, help your doctor determine whether lupus or another autoimmune disease is present.
How often should I retest my ANA levels?
If you're initially negative but symptoms persist or worsen, your doctor may recommend retesting in 3-6 months, as autoimmune markers can develop over time. If you're diagnosed with lupus, retesting frequency depends on your disease activity and treatment—typically every 3-6 months during active disease or medication adjustments, and annually when stable. Your rheumatologist will create a personalized monitoring schedule based on your specific situation, symptoms, and response to treatment.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
ANA (Antinuclear Antibody) Negative
Demo results
Negative Positive
Negative

What this means

Your ANA test came back negative, meaning no significant antinuclear antibodies were detected in your blood. This is the expected and healthy result, suggesting that lupus or other ANA-related autoimmune conditions are unlikely at this time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Joint Pain, Fatigue, and Lupus Symptoms

Google
3,141 reviews
  • Checks for lupus-related antibodies
  • Identifies autoimmune disease indicators
  • Analyzes blood for lupus markers

1,000,000+ blood tests later, here's what our customers say

Google reviews 3141 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.