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LD Isoenzymes test for detecting tissue damage in heart, liver, and other organs

Blood Test for Heart and Liver Enzyme Levels

Lactate Dehydrogenase (LD) Isoenzymes Test Panel

Google
3,138 reviews
  • Checks enzyme levels in blood
  • Detects tissue damage or disease
  • Monitors heart and liver health
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained symptoms like chest pain, fatigue, or signs of organ damage and your doctor needs to pinpoint the source. LD isoenzymes help identify which specific tissue or organ is affected—whether it's your heart, liver, lungs, or kidneys—by measuring different forms of the lactate dehydrogenase enzyme. It's commonly ordered when other tests show elevated LD levels but more detailed information is needed to guide treatment.

How should I prepare for this test?

No fasting is needed for this test, making it convenient to schedule at any time of day. You can eat and drink normally before your blood draw. Simply arrive at the lab during their operating hours with your test order, and the blood sample collection takes just a few minutes.

What's included in this test?

This test measures five different forms of the lactate dehydrogenase enzyme (LD1, LD2, LD3, LD4, and LD5), each predominantly found in specific tissues throughout your body. By analyzing the pattern and levels of these isoenzymes, doctors can identify whether damage or disease is affecting your heart, liver, lungs, kidneys, or red blood cells. This targeted approach provides much more specific diagnostic information than a total LD test alone, helping pinpoint the exact source of health concerns.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your LD isoenzyme pattern reveals about potential tissue damage or disease. These notes include personalized recommendations on whether you need follow-up testing, specialist referrals, or lifestyle modifications based on which organs are affected. You'll also get the standard lab report and can track your enzyme levels over time using our trends feature, which is especially helpful for monitoring treatment progress or disease management.
Who should consider getting this test?
This test is typically ordered for people with elevated total LD levels who need more specific information about where tissue damage is occurring. It's valuable for those experiencing chest pain, shortness of breath, unexplained fatigue, jaundice, or other symptoms suggesting organ damage. Doctors also use it to monitor certain types of anemia, cancer progression, or recovery from heart attack or liver disease.
What symptoms indicate I may need this test?
You may need this test if you're experiencing chest pain or tightness that could indicate heart problems, persistent fatigue that might signal anemia or organ disease, or yellowing of the skin suggesting liver issues. Other symptoms include unexplained shortness of breath, muscle weakness, dark urine, or abdominal pain that could point to damage in various organs. This test helps your doctor determine which organ system needs attention.
What is lactate dehydrogenase and why does it matter?
Lactate dehydrogenase (LD) is an enzyme found in nearly all body tissues that helps convert sugar into energy. When cells are damaged or destroyed—whether from disease, injury, or reduced oxygen supply—LD is released into the bloodstream. Measuring the different forms (isoenzymes) of LD helps doctors identify which specific organ or tissue is damaged, making it a valuable diagnostic tool for heart attacks, liver disease, certain cancers, and blood disorders.
What does high LD mean for different organs?
High LD1 and LD2 typically indicate heart or red blood cell damage, such as from a heart attack or hemolytic anemia. Elevated LD3 suggests lung tissue damage or certain white blood cell disorders. High LD4 and LD5 usually point to liver disease, muscle injury, or damage to other organs. The specific pattern of which isoenzymes are elevated helps your doctor pinpoint exactly where the problem is located.
How can I naturally support healthy LD levels?
Supporting healthy LD levels means protecting your organs from damage through heart-healthy lifestyle choices like regular exercise, a balanced diet rich in fruits and vegetables, and avoiding excessive alcohol. Managing chronic conditions like diabetes and high blood pressure reduces organ stress. Getting adequate rest, staying hydrated, and avoiding toxins that damage the liver or kidneys all help maintain healthy tissue function and normal enzyme levels.
How often should I retest LD isoenzymes?
Retesting frequency depends on why the test was ordered initially. If monitoring recovery from a heart attack or acute illness, your doctor may retest within days to weeks to track healing progress. For chronic conditions like liver disease or certain cancers, testing every few months helps monitor disease progression or treatment effectiveness. If your results were normal and you're asymptomatic, routine retesting typically isn't needed unless new symptoms develop.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
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Instant orders, results often overnight*
Results explained in simple language
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No insurance needed, transparent pricing
Demo results
LD1 (Lactate Dehydrogenase Isoenzyme 1) 28%
Demo results
Low Optimal 14 - 26% High
28%

What this means

Your LD1 isoenzyme is elevated above the optimal range, which may indicate stress or damage to your heart tissue or red blood cells. While this requires medical evaluation to determine the exact cause, it could be related to recent cardiac issues, hemolytic anemia, or other conditions affecting these tissues.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Heart and Liver Enzyme Levels

Google
3,138 reviews
  • Checks enzyme levels in blood
  • Detects tissue damage or disease
  • Monitors heart and liver health

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.