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IgD blood test for diagnosing rare immune disorders and myeloma screening

Blood Test for Immune System Issues and Recurrent Fevers

IgD

Google
3,138 reviews
  • Checks immune system protein levels.
  • Detects IgD antibody in blood.
  • Helps diagnose immune system disorders.
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if your doctor suspects you have a rare immune system disorder or certain types of blood cancers like multiple myeloma. It measures IgD, a type of antibody that's normally present at very low levels but can be extremely high in some conditions. This test helps doctors diagnose hyperimmunoglobulinemia IgD syndrome (HIDS), which causes recurrent fevers and inflammation, or detect certain types of myeloma that produce excessive IgD antibodies.

How should I prepare for this test?

No special preparation is typically required for the IgD blood test. You can eat and drink normally before your appointment and take your regular medications unless your healthcare provider gives you specific instructions otherwise. Simply arrive at the lab during their operating hours for your blood draw.

What's included in this test?

IgD

This test measures IgD (Immunoglobulin D), a specific type of antibody protein that accounts for less than 1% of total immunoglobulins in healthy individuals. Measuring IgD levels helps identify rare immune disorders like hyperimmunoglobulinemia IgD syndrome and certain types of multiple myeloma where IgD production becomes abnormally elevated. This specialized measurement provides crucial diagnostic information that standard immune panels don't typically include.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your IgD levels mean for your immune system health and whether further investigation is needed. These notes include personalized recommendations about next steps, such as consulting with an immunologist or hematologist if levels are abnormal, or whether additional testing is warranted. You'll also get the standard lab report and can track your IgD levels over time using our trends feature, which is especially helpful if you're monitoring a diagnosed condition or treatment effectiveness.
When will I get my results?
Results for the IgD test are typically available within 3-5 business days after your blood sample reaches the laboratory. You'll be notified as soon as your results are ready and can access them through your secure online account along with the doctor notes explaining what your levels mean.
Who should consider getting this test?
This test is typically ordered by doctors for people experiencing recurrent unexplained fevers, persistent inflammation, enlarged lymph nodes, or symptoms suggesting a plasma cell disorder. It's also considered for patients with suspected multiple myeloma or monoclonal gammopathy, or for those with a family history of rare immune disorders. This is a specialized test usually recommended when other immune markers suggest an unusual condition.
What symptoms indicate I may need this test?
Symptoms that might prompt your doctor to order this test include recurring fevers that come and go without clear cause, persistent joint pain and inflammation, unexplained abdominal pain, skin rashes during fever episodes, or enlarged lymph nodes or spleen. Additionally, symptoms like unexplained weight loss, bone pain, frequent infections, or extreme fatigue that suggest a blood disorder might warrant this specialized immune testing.
What is IgD and why does it matter?
IgD (Immunoglobulin D) is one of five classes of antibodies your immune system produces, though it normally exists at very low levels in your blood. While its exact function isn't completely understood, abnormally high IgD levels can signal serious conditions like multiple myeloma (a blood cancer) or hyperimmunoglobulinemia IgD syndrome (a genetic inflammatory disorder). Measuring IgD helps doctors diagnose these rare but important conditions that might otherwise be missed.
What does high IgD mean?
Very high IgD levels most commonly indicate multiple myeloma, a type of blood cancer where plasma cells produce excessive amounts of this antibody. Elevated IgD can also signal hyperimmunoglobulinemia IgD syndrome (HIDS), a rare genetic condition causing recurrent fevers and inflammation. If your IgD is high, your doctor will likely recommend additional tests to determine the underlying cause and appropriate treatment.
What happens if my IgD results are abnormal?
If your IgD levels are abnormally high, your doctor will likely refer you to a specialist such as a hematologist or immunologist for further evaluation. Additional testing may include bone marrow biopsy, imaging studies, genetic testing, or other blood work to confirm a diagnosis. Treatment depends on the underlying condition identified and may range from anti-inflammatory medications for HIDS to chemotherapy or targeted therapies for myeloma.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
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US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
IgD (Immunoglobulin D) 185 mg/dL
Demo results
Normal < 10 Elevated ≥ 10
185 mg/dL

What this means

Your IgD level is significantly elevated above the normal range. While healthy individuals typically have very low IgD levels (under 10 mg/dL), elevated levels may indicate a rare immune disorder or require further investigation for conditions like multiple myeloma or hyperimmunoglobulinemia IgD syndrome.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Immune System Issues and Recurrent Fevers

Google
3,138 reviews
  • Checks immune system protein levels.
  • Detects IgD antibody in blood.
  • Helps diagnose immune system disorders.

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.