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Genetic test for Factor V Leiden mutation to assess blood clot risk

Genetic Test for Blood Clots and Clotting Disorders

Factor V (Leiden) Mutation Analysis

Google
3,138 reviews
  • Checks for blood clotting disorder gene.
  • Identifies genetic risk for clots.
  • Detects mutation causing clotting issues.
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you've experienced unexplained blood clots, have a family history of clotting disorders, or are planning pregnancy or surgery. It identifies a specific genetic mutation that increases your tendency to form abnormal blood clots in veins, particularly in the legs or lungs. Many people use this test when they want to understand their clotting risk before making decisions about birth control, hormone therapy, or long flights.

What's included in this test?

Factor V (Leiden) Mutation

This genetic test analyzes your DNA to detect the specific Factor V Leiden mutation, which is the most common inherited blood clotting disorder. The mutation affects how your blood clots, making it more likely to form clots in veins, especially during periods of immobility, pregnancy, or when taking estrogen-containing medications. Understanding your genetic status helps you and your doctor make informed decisions about medical treatments and lifestyle choices that affect clotting risk.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining whether you carry the Factor V Leiden mutation and what it means for your clotting risk. These notes include personalized recommendations about lifestyle precautions, when to use blood thinners, and considerations for pregnancy or contraceptive choices. You'll also get the standard lab report and can share this genetic information with family members who may want to get tested.

Who should consider getting this test?
This test is recommended if you've had unexplained blood clots, especially before age 50, or if close family members have had clotting disorders. It's also important for women considering birth control pills or hormone replacement therapy, anyone planning major surgery, and people with a personal or family history of deep vein thrombosis or pulmonary embolism. Pregnant women or those planning pregnancy with risk factors should also consider testing.
What symptoms indicate I may need this test?
Signs include unexplained leg swelling, pain, or warmth (especially in one leg), sudden shortness of breath or chest pain, or a history of blood clots after surgery or pregnancy. You may also need testing if you've had multiple miscarriages, have family members with early-onset clots, or experience clotting while taking birth control pills. However, many people with the mutation have no symptoms until a clot occurs.
How can I reduce my risk of blood clots with Factor V Leiden?
Stay active and avoid prolonged sitting during travel by moving around every hour or wearing compression socks. Maintain a healthy weight, stay well-hydrated, and avoid smoking, which significantly increases clot risk. During high-risk periods like surgery or pregnancy, your doctor may recommend blood thinners. Regular exercise, leg elevation, and avoiding estrogen-containing medications when possible also help manage risk.
What is Factor V Leiden and why does it matter?
Factor V Leiden is a genetic mutation that affects one of the clotting factors in your blood, making it resistant to a natural anticlotting process. This means your blood clots more easily than normal, increasing risk for deep vein thrombosis and pulmonary embolism. While many people with the mutation never develop clots, knowing your status helps you avoid high-risk situations and make informed medical decisions.
What does a positive result mean?
A positive result means you carry one or two copies of the Factor V Leiden mutation. Having one copy (heterozygous) increases your clotting risk 3-8 times, while two copies (homozygous) increase it even more. This doesn't mean you'll definitely get a blood clot, but you should take precautions during high-risk situations like long flights, surgery, or pregnancy, and discuss birth control options with your doctor.
What does a negative result mean?
A negative result means you don't carry the Factor V Leiden mutation, which is the most common genetic cause of abnormal blood clotting. However, this doesn't completely rule out other clotting disorders or eliminate your risk for blood clots from other causes like prolonged immobility, surgery, or certain medications. If you've had unexplained clots, your doctor may recommend testing for other clotting disorders.
How often should I retest for Factor V Leiden?
You only need this genetic test once in your lifetime, as your DNA doesn't change. The result is permanent and doesn't require retesting. However, if you test positive, your doctor may recommend periodic monitoring of other blood clotting factors or regular check-ups during high-risk periods like pregnancy or before surgery to ensure proper management of your clotting risk.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Factor V Leiden Mutation Not Detected
Demo results
Not Detected Detected
Not Detected

What this means

Your test shows that you do not carry the Factor V Leiden mutation, which is the most common inherited cause of abnormal blood clotting. This is a normal and reassuring result, meaning you do not have this particular genetic risk factor for developing blood clots.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Genetic Test for Blood Clots and Clotting Disorders

Google
3,138 reviews
  • Checks for blood clotting disorder gene.
  • Identifies genetic risk for clots.
  • Detects mutation causing clotting issues.

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.